Dengue is a tropical disease caused by an arbovirus transmitted by Aedes aegypti. Since no
effective vaccine is available for treating dengue, the present study focused on population …

Grandisin, a lignan isolated from many species of plants, such as Virola surinamensis, is a
potential drug candidate due to its biological properties, highlighted by its antitumor and …

Biological activity of neolignans on the post-embryonic development of Chrysomya
megacephala - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …

Phytochemical investigation of the methanol extract of Euchresta formosana resulted in the
isolation of thirty-four compounds. Compounds 1, 3-12, 15, 27, 29 and 32-24 were isolated …

Mild iodination using iodine and a 30% solution of hydrogen peroxide as oxidant was
performed in water. The method proved to be efficient and selective for the introduction of …

Chemical scaffolds of natural products have historically been sources of inspiration for the
development of novel molecules of biological relevance, including hit and lead compounds …

(−)‐grandisin is a tetrahydrofuran lignan that displays important biological properties, such
as trypanocidal, anti‐inflammatory, cytotoxic, and antitumor activities, suggesting its utility as …

Lignans represent a well-known group of natural products with anti-protozoal activity. In the
literature there are many examples of the anti-parasitic activity of synthetic analogues of …

A series of 2-aryl and 2, 5-diarylfurans were synthesized and evaluated for their in vitro
cytotoxicity against human cancer cells lines and on the proliferation of human peripheral …

Objectives The chemoprotective effect of the tetrahydrofuran lignan grandisin against DNA
damage induced by cyclophosphamide (200 mg/kg) has been evaluated using the in vitro …