[HTML][HTML] Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis

C Cao, M Yu, Y Chai - Cell death & disease, 2019 - nature.com
Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulated host
response to infection that leads to uncontrolled inflammatory response followed by …

[HTML][HTML] Exploring the Role of Staphylococcus aureus in Inflammatory Diseases

H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

Apoptosis: A review of pro‐apoptotic and anti‐apoptotic pathways and dysregulation in disease

MA O'Brien, R Kirby - … of veterinary emergency and critical care, 2008 - Wiley Online Library
Objective–To review the human and veterinary literature on the biology of apoptosis in
health and disease. Data Sources–Data were examined from the human and veterinary …

[HTML][HTML] Mitochondrial mechanisms of sepsis-induced organ failure

MC Exline, ED Crouser - Frontiers in bioscience: a journal and …, 2008 - ncbi.nlm.nih.gov
Sepsis is the leading cause of death in medical intensive care units. Though progress has
been made in the early treatment of sepsis associated with hemodynamic collapse (septic …

[HTML][HTML] Apoptosis induced by Staphylococcus aureus toxins

X Zhang, X Hu, X Rao - Microbiological research, 2017 - Elsevier
Apoptosis stimulated by bacterial toxins is common during infection and is now considered
important in disease processes. As a major human pathogen, Staphylococcus aureus also …

[HTML][HTML] Circulating plasma factors induce tubular and glomerular alterations in septic burns patients

F Mariano, V Cantaluppi, M Stella, GM Romanazzi… - Critical care, 2008 - Springer
Background Severe burn is a systemic illness often complicated by sepsis. Kidney is one of
the organs invariably affected, and proteinuria is a constant clinical finding. We studied the …

The Nuclear Hormone Receptor PPARγ as a Therapeutic Target in Major Diseases

MV Schmidt, B Brüne… - The Scientific World …, 2010 - Wiley Online Library
The peroxisome proliferator‐activated receptor γ (PPARγ) belongs to the nuclear hormone
receptor superfamily and regulates gene expression upon heterodimerization with the …

Rationally designed peptide regulators of protein kinase C

EN Churchill, N Qvit, D Mochly-Rosen - Trends in Endocrinology & …, 2009 - cell.com
Protein–protein interactions sequester enzymes close to their substrates. Protein kinase C
(PKC) is one example of a ubiquitous signaling molecule with effects that are dependent …

[HTML][HTML] Complementary mechanisms potentially involved in the pathology of Zika virus

CR Ojha, M Rodriguez, J Lapierre… - Frontiers in …, 2018 - frontiersin.org
Zika virus (ZIKV) has emerged as a global health threat due to its neuro-teratogenic effect
and wide range of transmission routes. Most recently, ZIKV infection has been linked with …

Cellular processes in sepsis

A Rudiger, M Stotz, M Singer - Swiss Medical Weekly, 2008 - zora.uzh.ch
Sepsis, the systemic inflammatory response to an infection, is an increasingly common
condition. It represents a major healthcare problem as affected patients have a high …