Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and …

Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …

Autophagy is a conserved method of quality control in which cytoplasmic contents are
degraded via lysosomes. Lipophagy, a form of selective autophagy and a novel type of lipid …

Macroautophagy is an evolutionarily conserved process that delivers diverse cellular
contents to lysosomes for degradation. As our understanding of this pathway grows, so does …

Lipid droplets are cytosolic fat storage organelles present in most eukaryotic cells. Long
regarded merely as inert fat reservoirs, they are now emerging as major regulators of …

Autophagy is a conserved pathway that delivers cytoplasmic contents to the lysosome for
degradation. Here we consider its roles in neuronal health and disease. We review …

Knowledge of lipid droplets (LDs) has evolved from simple depots of lipid storage to
dynamic and functionally active organelles involved in a variety of cellular functions. Studies …

Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …

Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to …