[HTML][HTML] The machinery of exosomes: biogenesis, release, and uptake

SV Krylova, D Feng - International Journal of Molecular Sciences, 2023 - mdpi.com
Exosomes are a subtype of membrane-contained vesicles 40–200 nm in diameter that are
secreted by cells into their surroundings. By transporting proteins, lipids, mRNA, miRNA …

The power and potential of mitochondria transfer

N Borcherding, JR Brestoff - Nature, 2023 - nature.com
Mitochondria are believed to have originated through an ancient endosymbiotic process in
which proteobacteria were captured and co-opted for energy production and cellular …

[HTML][HTML] β-Coronaviruses use lysosomes for egress instead of the biosynthetic secretory pathway

S Ghosh, TA Dellibovi-Ragheb, A Kerviel, E Pak, Q Qiu… - Cell, 2020 - cell.com
Summary β-Coronaviruses are a family of positive-strand enveloped RNA viruses that
includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is …

Extracellular vesicles in cancer—implications for future improvements in cancer care

R Xu, A Rai, M Chen, W Suwakulsiri… - Nature reviews Clinical …, 2018 - nature.com
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …

[HTML][HTML] Focus on extracellular vesicles: introducing the next small big thing

H Kalra, GPC Drummen, S Mathivanan - International journal of molecular …, 2016 - mdpi.com
Intercellular communication was long thought to be regulated exclusively through direct
contact between cells or via release of soluble molecules that transmit the signal by binding …

Pollutants bioavailability and toxicological risk from microplastics to marine mussels

CG Avio, S Gorbi, M Milan, M Benedetti, D Fattorini… - Environmental …, 2015 - Elsevier
Microplastics represent a growing environmental concern for the oceans due to their
potential of adsorbing chemical pollutants, thus representing a still unexplored source of …

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

E Cocucci, J Meldolesi - Trends in cell biology, 2015 - cell.com
Long-and short-distance communication can take multiple forms. Among them are
exosomes and ectosomes, extracellular vesicles (EVs) released from the cell to deliver …

[HTML][HTML] ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins

C Villarroya-Beltri, F Baixauli, M Mittelbrunn… - Nature …, 2016 - nature.com
Exosomes are vesicles secreted to the extracellular environment through fusion with the
plasma membrane of specific endosomes called multivesicular bodies (MVB) and mediate …

[HTML][HTML] The position of lysosomes within the cell determines their luminal pH

DE Johnson, P Ostrowski, V Jaumouillé… - The Journal of cell …, 2016 - ncbi.nlm.nih.gov
We examined the luminal pH of individual lysosomes using quantitative ratiometric
fluorescence microscopy and report an unappreciated heterogeneity: peripheral lysosomes …

[HTML][HTML] Multiple roles of the small GTPase Rab7

F Guerra, C Bucci - Cells, 2016 - mdpi.com
Rab7 is a small GTPase that belongs to the Rab family and controls transport to late
endocytic compartments such as late endosomes and lysosomes. The mechanism of action …