Simple Summary In colorectal cancer cells, reducing the essential amino acid methionine in
the culture medium led to an increase in two markers of response to immune checkpoint …

During infection, Salmonella hijacks essential host signaling pathways. These molecular
manipulations disrupt cellular integrity and may induce oncogenic transformation. Systemic …

Patient-derived organoid models are proving to be a powerful platform for both basic and
translational studies. Here we conduct a methodical analysis of pancreatic ductal …

Production of local microbubbles (MBs) with dense distribution in tumor environment is
achieved by developing an integrated electrochemical stimulator on a microfabricated …

Percutaneous locoregional therapies (LRTs), such as thermal ablation, are performed to
limit the progression of hepatocellular carcinoma (HCC) and offer a bridge for patients …

Although thousands of solid tumors have been sequenced to date, a fundamental under-
sampling bias is inherent in current methodologies. This is caused by a tissue sample input …

Even though cancer therapeutic methods are improving rapidly, cancer recurrence has
always remained a big challenge. Even a small lesion of missed neoplastic cells during the …

Lung cancer is one of the most common malignant cancers worldwide. Searching for
specific cancer targets and developing efficient therapies with lower toxicity is urgently …

Therapeutic targeting of tumor cells with drug nanocarriers relies upon successful interaction
with membranes and efficient cell internalization. A further consideration is that engineered …

Glioblastoma multiforme (GBM) is a fatal brain tumor characterized by infiltration beyond the
margins of the main tumor mass and local recurrence after surgery. The blood-brain barrier …