Abstract The United States Food and Drug Administration (US FDA) has always been a
forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs …

Bacterial infectious diseases are one of the leading causes of death worldwide. Even with
the use of multiple antibiotic treatment strategies, 4.95 million people died from drug …

Urinary tract infection is among the most common infections worldwide, typically studied in
animals and cell lines with limited uropathogenic strains. Here, we assessed diverse …

TcpC is a multifunctional virulence factor of Uropathogenic Escherichia coli (UPEC).
Macrophages can differentiate into two different subsets M1 and M2 that play distinct roles in …

Complicated Urinary Tract Infections - Abstract - Europe PMC Sign in | Create an account
https://orcid.org Europe PMC Menu About Tools Developers Help Contact us Helpdesk …

Urinary tract infections (UTIs) are prevalent worldwide, particularly among women. Their
incidence increases with age, and treatment is increasingly challenging owing to antibiotic …

Helicobacter pylori infections are responsible for tremendous morbidity and mortality
worldwide, leading to efforts to eradicate the organism. However, the effectiveness of …

Objectives Uncomplicated urinary tract infections (uUTIs) are a common problem in female
patients. Management is mainly based on empirical prescribing, but there are concerns …

We rationally designed a bacteriophage cocktail to treat a 56-year-old male liver transplant
patient with complex, recurrent prostate and urinary tract infections caused by an extended …

Introduction Empirical therapy for the treatment of urinary tract infections should be tailored
to the current distribution and susceptibility of potential pathogens to ensure optimal …