[HTML][HTML] Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021
Q Wu, W Qian, X Sun, S Jiang - Journal of hematology & oncology, 2022 - Springer
Abstract The United States Food and Drug Administration (US FDA) has always been a
forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs …
forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs …
Immunomodulatory biomaterials against bacterial infections: Progress, challenges, and future perspectives
S Zhang, H Yang, M Wang, D Mantovani, K Yang… - The Innovation, 2023 - cell.com
Bacterial infectious diseases are one of the leading causes of death worldwide. Even with
the use of multiple antibiotic treatment strategies, 4.95 million people died from drug …
the use of multiple antibiotic treatment strategies, 4.95 million people died from drug …
A human urothelial microtissue model reveals shared colonization and survival strategies between uropathogens and commensals
Urinary tract infection is among the most common infections worldwide, typically studied in
animals and cell lines with limited uropathogenic strains. Here, we assessed diverse …
animals and cell lines with limited uropathogenic strains. Here, we assessed diverse …
[HTML][HTML] TcpC inhibits M1 but promotes M2 macrophage polarization via regulation of the MAPK/NF-κB and Akt/STAT6 pathways in urinary tract infection
J Fang, Q Ou, B Wu, S Li, M Wu, J Qiu, N Cen, K Hu… - Cells, 2022 - mdpi.com
TcpC is a multifunctional virulence factor of Uropathogenic Escherichia coli (UPEC).
Macrophages can differentiate into two different subsets M1 and M2 that play distinct roles in …
Macrophages can differentiate into two different subsets M1 and M2 that play distinct roles in …
[HTML][HTML] Complicated urinary tract infections
A Sabih, SW Leslie - 2017 - europepmc.org
Complicated Urinary Tract Infections - Abstract - Europe PMC Sign in | Create an account
https://orcid.org Europe PMC Menu About Tools Developers Help Contact us Helpdesk …
https://orcid.org Europe PMC Menu About Tools Developers Help Contact us Helpdesk …
[HTML][HTML] SUsceptibility and Resistance to Fosfomycin and other antimicrobial agents among pathogens causing lower urinary tract infections: findings of the SURF …
M Tutone, TEB Johansen, T Cai, S Mushtaq… - International Journal of …, 2022 - Elsevier
Urinary tract infections (UTIs) are prevalent worldwide, particularly among women. Their
incidence increases with age, and treatment is increasingly challenging owing to antibiotic …
incidence increases with age, and treatment is increasingly challenging owing to antibiotic …
Cross-roads for meta-analysis and network meta-analysis of H. pylori therapy
DY Graham, R Hernaez, T Rokkas - Gut, 2022 - gut.bmj.com
Helicobacter pylori infections are responsible for tremendous morbidity and mortality
worldwide, leading to efforts to eradicate the organism. However, the effectiveness of …
worldwide, leading to efforts to eradicate the organism. However, the effectiveness of …
[HTML][HTML] A global perspective on improving patient care in uncomplicated urinary tract infection: expert consensus and practical guidance
Objectives Uncomplicated urinary tract infections (uUTIs) are a common problem in female
patients. Management is mainly based on empirical prescribing, but there are concerns …
patients. Management is mainly based on empirical prescribing, but there are concerns …
[HTML][HTML] Phage therapy related microbial succession associated with successful clinical outcome for a recurrent urinary tract infection
We rationally designed a bacteriophage cocktail to treat a 56-year-old male liver transplant
patient with complex, recurrent prostate and urinary tract infections caused by an extended …
patient with complex, recurrent prostate and urinary tract infections caused by an extended …
[HTML][HTML] Antimicrobial resistance of clinical Enterobacterales isolates from urine samples, Germany, 2016 to 2021
C Stoltidis-Claus, KD Rosenberger… - …, 2023 - eurosurveillance.org
Introduction Empirical therapy for the treatment of urinary tract infections should be tailored
to the current distribution and susceptibility of potential pathogens to ensure optimal …
to the current distribution and susceptibility of potential pathogens to ensure optimal …