Intermittent hypoxia (IH) is a hallmark manifestation of obstructive sleep apnea (OSA), a
widespread disorder of breathing. This Review focuses on the role of hypoxia-inducible …

Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

Population-based epidemiologic studies have uncovered the high prevalence and wide
severity spectrum of undiagnosed obstructive sleep apnea, and have consistently found that …

Disordered breathing during sleep is associated with acute, unfavorable effects on
cardiovascular physiology, but few studies have examined its postulated association with …

Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened
over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally …

This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …

Objective: To provide an overview of the healthcare and societal consequences and costs of
untreated obstructive sleep apnea syndrome. Data sources: PubMed database for English …

Pheochromocytoma and paraganglioma (PPGL) require prompt consideration and efficient
diagnosis and treatment to minimize associated morbidity and mortality. Once considered …

Obstructive sleep apnoea syndrome (OSA) is associated with increased cardiovascular
morbidity and mortality. However, the underlying mechanisms are not entirely understood …

Clinic-based studies suggest that sleep-disordered breathing (SDB) is associated with
glucose intolerance and insulin resistance. However, in the available studies, researchers …