Recent advances in genomics have revealed a wide spectrum of genetic variants
associated with neurodevelopmental disorders at an unprecedented scale. An increasing …

The main neurotransmitter in the brain responsible for the inhibition of neuronal activity is γ-
aminobutyric acid (GABA). It plays a crucial role in circuit formation during development …

The excitatory/inhibitory (E/I) imbalance hypothesis posits that imbalance between excitatory
(glutamatergic) and inhibitory (GABAergic) mechanisms underlies the behavioral …

Altered reactivity and responses to auditory input are core to the diagnosis of autism
spectrum disorder (ASD). Preclinical models implicate ϒ-aminobutyric acid (GABA) in this …

Brain dynamic functional connectivity characterises transient connections between brain
regions. Features of brain dynamics have been linked to emotion and cognition in adult …

Clinical trials of pharmacological candidates targeting the core features of autism have
largely failed. This is despite evidence linking differences in multiple neurochemical systems …

Objective: Autism spectrum disorder (ASD) affects nearly 1 in 44 children younger than 8
years old in the United States, and the situation may be even worse in remote areas of the …

The efficiency of neocortical information processing critically depends on the balance
between the glutamatergic (excitatory, E) and GABAergic (inhibitory, I) synaptic …

Introduction During observation of the ambiguous Necker cube, our perception suddenly
reverses between two about equally possible 3D interpretations. During passive …

Brain functional dynamics have been linked to emotion and cognition in mature individuals,
where alterations are associated with mental ill-health and neurodevelopmental conditions …