Rheological abnormalities in human erythrocytes subjected to oxidative inflammation

T Maruyama, M Hieda, S Mawatari, T Fujino - Frontiers in Physiology, 2022 - frontiersin.org
Erythrocytes are oxygen carriers and exposed to redox cycle in oxygenation and
deoxygenation of hemoglobin. This indicates that circulating erythrocytes are vulnerable to …

Mercury chloride affects band 3 protein-mediated anionic transport in red blood cells: Role of oxidative stress and protective effect of olive oil polyphenols

P Perrone, S Spinelli, G Mantegna, R Notariale… - Cells, 2023 - mdpi.com
Mercury is a toxic heavy metal widely dispersed in the natural environment. Mercury
exposure induces an increase in oxidative stress in red blood cells (RBCs) through the …

Superoxide: A major role in the mechanism of action of essential antimalarial drugs

CO Egwu, I Tsamesidis, P Pério, JM Augereau… - Free Radical Biology …, 2021 - Elsevier
Understanding the mode of action of antimalarials is central to optimizing their use and the
discovery of new therapeutics. Currently used antimalarials belong to a limited series of …

Syk Kinase Inhibitors Synergize with Artemisinins by Enhancing Oxidative Stress in Plasmodium falciparum-Parasitized Erythrocytes

I Tsamesidis, K Reybier, G Marchetti, MC Pau, P Virdis… - Antioxidants, 2020 - mdpi.com
Although artemisinin-based combination therapies (ACTs) treat Plasmodium falciparum
malaria effectively throughout most of the world, the recent expansion of ACT-resistant …

AAPH-induced oxidative damage reduced anion exchanger 1 (SLC4A1/AE1) activity in human red blood cells: Protective effect of an anthocyanin-rich extract

A Remigante, S Spinelli, GT Patanè, D Barreca… - Frontiers in …, 2023 - frontiersin.org
Introduction: During their lifespan in the bloodstream, red blood cells (RBCs) are exposed to
multiple stressors, including increased oxidative stress, which can affect their morphology …

Determination of hydrogen peroxide released from cancer cells by a Fe-Organic framework/horseradish peroxidase-modified electrode

T Jiang, X Sun, L Wei, M Li - Analytica Chimica Acta, 2020 - Elsevier
Multi-walled carbon nanotubes (MWCNTs) were used as conductive carrier on the glassy
carbon electrode (GCE), and the hybrid of metal organic framework [NH 2-MIL-53 (Fe)] and …

3, 4-Dihydroxybenzaldehyde mitigates fluoride-induced cytotoxicity and oxidative damage in human RBC

R Anjum, N Maheshwari, R Mahmood - … of Trace Elements in Medicine and …, 2022 - Elsevier
Background Fluoride is an essential micronutrient that is needed for mineralization of bones
and formation of dental enamel. It is a widely dispersed environmental pollutant and chronic …

Dinuclear and mononuclear metal(II) polypyridyl complexes against drug-sensitive and drug-resistant Plasmodium falciparum and their mode of action

JW Lai, MJ Maah, KW Tan, R Sarip, YAL Lim… - Malaria journal, 2022 - Springer
Background Malaria remains one of the most virulent and deadliest parasitic disease in the
world, particularly in Africa and Southeast Asia. Widespread occurrence of artemisinin …

In vitro and in silico antimalarial evaluation of FM-AZ, a new artemisinin derivative

I Tsamesidis, F Mousavizadeh, CO Egwu… - Medicines, 2022 - mdpi.com
Artemisinin-based Combination Therapies (ACTs) are currently the frontline treatment
against Plasmodium falciparum malaria, but parasite resistance to artemisinin (ART) and its …

[PDF][PDF] Redox Status of Erythrocytes as an Important Factor in Eryptosis and Erythronecroptosis.

A Tkachenko, O Havránek - Folia Biologica (00155500), 2023 - foliabiologica.lf1.cuni.cz
Overall, reactive oxygen species (ROS) signalling significantly contributes to initiation and
modulation of multiple regulated cell death (RCD) pathways. Lately, more information has …