Biomedical engineers have traditionally developed technologies in response to the needs of
the developed world's medical community. As a result, the diagnostic systems on which they …

As drug-resistant falciparum malaria has continued to evolve and spread worldwide,
artemisinin-based combination therapies (ACT) have become the centerpiece of global …

To limit the spread and impact of anti-malarial drug resistance and react accordingly,
surveillance systems able to detect and track in real-time its emergence and spread need to …

Background After many years of general neglect, interest has grown and efforts came under
way for the mapping, control, surveillance, and eventual elimination of neglected tropical …

Among the various determinants of treatment response, the achievement of sufficient blood
levels is essential for curing malaria. For helping us at improving our current understanding …

Background. Plasmodium falciparum malaria resistant to chloroquine and pyrimethamine
originated in limited foci and migrated to Africa. It remains unresolved whether P. falciparum …

ABSTRACT The involvement of Pfmdr1 (Plasmodium falciparum multidrug resistance 1)
polymorphisms in antimalarial drug resistance is still debated. Here, we evaluate the …

Background Artesunate and amodiaquine (AS&AQ) is at present the world's second most
widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the …

Polymorphisms in the Plasmodium falciparum crt (Pf crt), Pf mdr1, and Pf mrp genes were
not significantly associated with quinine (QN) 50% inhibitory concentrations (IC50s) in 23 …

Résumé Au cours de leur évolution, les micro-organismes ont su déjouer les pièges qui leur
sont tendus par l'environnement et notamment leur hôte (immunité et utilisation de …