Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …

Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …

CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …

Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …

Purpose To summarize definitions, prevalence, risk factors, consequences, and acute
management of seizure clusters using rescue medications. Methods We searched MEDLINE …

Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …

Background Tonic‐clonic convulsions and convulsive status epilepticus (currently defined
as a tonic‐clonic convulsion lasting at least 30 minutes) are medical emergencies and …

The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …

Background Episodes of childhood convulsive status epilepticus (CSE) commonly start in
the community. Treatment of CSE aims to minimise the length of seizures, treat the causes …

Background: Rapid treatment of status epilepticus (SE) is associated with better outcomes.
Diazepam and midazolam are commonly used, but the optimal agent and administration …