New flow cytometric assays for monitoring cell-mediated cytotoxicity

L Zaritskaya, MR Shurin, TJ Sayers… - Expert review of …, 2010 - Taylor & Francis
The exact immunologic responses after vaccination that result in effective antitumor
immunity have not yet been fully elucidated and the data from ex vivo T-cell assays have not …

“To B or not to B?” B-cells and graft rejection

V Zarkhin, L Li, M Sarwal - Transplantation, 2008 - journals.lww.com
There is increasing evidence that various maturational stages of B-cells infiltrate various
solid organ transplants undergoing acute rejection. The presence of immature CD20+ and …

Immunobiology of naïve and genetically modified HLA-class-I-knockdown human embryonic stem cells

T Deuse, M Seifert, N Phillips, A Fire… - Journal of cell …, 2011 - journals.biologists.com
Human embryonic stem cells (hESCs) can serve as a universal cell source for emerging cell
or tissue replacement strategies, but immune rejection of hESC derivatives remains an …

Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival

T Deuse, M Seifert, N Phillips, A Fire, D Tyan, M Kay… - Circulation, 2011 - Am Heart Assoc
Background—Although human embryonic stem cells (hESC) have enormous potential for
cell replacement therapy of heart failure, immune rejection of hESC derivatives inevitably …

MHC class I recognition by monocyte-/macrophage-specific receptors

R Yoshida - Advances in immunology, 2014 - Elsevier
The most important transplantation antigens in the discrimination between “self” and
“nonself” are encoded by genes in the major histocompatibility complex (MHC) locus (H-2 in …

The Effect of Histological CD20‐Positive B Cell Infiltration in Acute Cellular Rejection on Kidney Transplant Allograft Survival

Y Jiang, R Wang, H Wang, H Huang… - Journal of …, 2016 - Wiley Online Library
Background. It is controversial whether lymphocyte infiltration exhibited in biopsy specimens
is associated with transplant outcomes. This study focused on the effect of CD20‐positive B …

Essential role of macrophages in the initiation of allergic rhinitis in mice sensitized intranasally once with cedar pollen: regulation of class switching of immunoglobulin …

M Hirano, H Ogita‐Nakanishi, W Miyachi… - Microbiology and …, 2012 - Wiley Online Library
The production of allergen‐specific IgE antibodies (Abs) in allergen‐sensitized patients or
animals has a mutual relationship with the immunologic response leading to allergic rhinitis …

Transgene number‐dependent, gene expression rate‐independent rejection of Dd‐, Kd‐, or DdKd‐transgened mouse skin or tumor cells from C57BL/6 (DbKb) mice

Y Inoue, J Tashiro‐Yamaji, M Hayashi… - Microbiology and …, 2011 - Wiley Online Library
Recipient cells migrating into the transplantation site of an allograft recognize
histocompatibility antigens on the grafts and are cytotoxic against the grafts. Although the …

Two types of allograft‐induced cytotoxic macrophage, one against allografts and the other against syngeneic or allogeneic tumor cells

Y Yoneda, J Tashiro‐Yamaji, T Kubota… - Microbiology and …, 2008 - Wiley Online Library
In the 1990s, based on the results of studies using β2M, CD4 or CD8 knockout mice, several
groups reported that the main effector cells responsible for skin or organ allograft rejection …

HLA-B62 as a possible ligand for the human homologue of mouse macrophage MHC receptor 2 (MMR2) on monocytes

T Shimizu, J Tashiro-Yamaji, M Hayashi, Y Inoue… - Gene, 2010 - Elsevier
We previously reported that a population of allograft (H-2DdKd)-induced macrophages (AIM)
in C57BL/6 (H-2DbKb) mice exhibited major histocompatibility complex (MHC) haplotype (H …