Cocaine exposure enhances permissiveness of quiescent T cells to HIV infection

SG Kim, JB Jung, D Dixit, R Rovner Jr… - Journal of leukocyte …, 2013 - academic.oup.com
In vivo and in vitro exposure to stimulants has been associated with increased levels of HIV
infection in PBMCs. Among these lymphocyte subsets, quiescent CD4+ T cells make up the …

Associations between use of crack cocaine and HIV-1 disease progression: research findings and implications for mother-to-infant transmission

JA Cook - Life sciences, 2011 - Elsevier
Recent in vitro and in vivo research has suggested that cocaine has a direct effect on the
pathogenesis of AIDS. These findings are confirmed by epidemiological studies linking the …

Optimizing treatment outcomes in HIV-infected patients with substance abuse issues

DD Celentano, G Lucas - Clinical infectious diseases, 2007 - academic.oup.com
Drug abuse is associated with poorer virologic and clinical outcomes for patients with
human immunodeficiency virus (HIV) infection. Limited evidence, primarily from in vitro and …

Methadone inhibits viral restriction factors and facilitates HIV infection in macrophages

MR Wang, DD Wu, F Luo, CJ Zhong, X Wang… - Frontiers in …, 2020 - frontiersin.org
Opioid abuse alters the functions of immune cells in both in vitro and in vivo systems,
including macrophages. Here, we investigated the effects of methadone, a widely used …

[HTML][HTML] Methamphetamine augments HIV-1 gp120 inhibition of synaptic transmission and plasticity in rat hippocampal slices: Implications for methamphetamine …

Y Zheng, B Reiner, J Liu, L Xu, H Xiong - Neurobiology of disease, 2022 - Elsevier
Methamphetamine (Meth) abuse and human immunodeficiency virus type 1 (HIV-1) infection
are two major public health problems worldwide. Being frequently comorbid with HIV-1 …

Cost of care for HIV‐infected patients with co‐occurring substance use disorder or psychiatric disease: report from a large, integrated health plan

GN DeLorenze, AL Tsai, MA Horberg… - AIDS research and …, 2014 - Wiley Online Library
Background. The costs of providing care to HIV‐infected (HIV+) patients with co‐occurring
diagnoses of substance use (SU) disorder or psychiatric disease (PD) are not well …

Methadone maintenance therapy and viral suppression among HIV-infected opioid users: the impacts of crack and injection cocaine use

ME Socías, E Wood, W Small, H Dong… - Drug and alcohol …, 2016 - Elsevier
Background Methadone maintenance therapy (MMT) is associated with improved HIV
treatment outcomes among people who use drugs (PWUD). The extent to which these …

Early immunologic and virologic responses to highly active antiretroviral therapy and subsequent disease progression among HIV-infected injection drug users

SH Mehta, G Lucas, J Astemborski, GD Kirk, D Vlahov… - Aids Care, 2007 - Taylor & Francis
We examined the prevalence and prognostic value of early responses to highly active
antiretroviral therapy (HAART) among community-based injection drug users (IDUs) in …

Probable deceleration of progression of Simian AIDS affected by opiate dependency: studies with a rhesus macaque/SIVsmm9 model

RM Donahoe, SP O'neil, FA Marsteller… - JAIDS Journal of …, 2009 - journals.lww.com
Objectives: To determine effects of opiate dependency on development of simian AIDS.
Design: Assessments of viral, immune, and clinicopathological status were conducted on …

Methamphetamine enhancement of HIV-1 gp120-mediated NLRP3 inflammasome activation and resultant proinflammatory responses in rat microglial cultures

D Dutta, J Liu, E Xu, H Xiong - International Journal of Molecular Sciences, 2024 - mdpi.com
Human Immunodeficiency Virus type 1 (HIV-1)-associated neurocognitive disorders
(HANDs) remain prevalent in HIV-1-infected individuals despite the evident success of …