Dissecting the integrative antioxidant and redox systems in plant mitochondria. Effect of stress and S-nitrosylation

JJ Lázaro, A Jiménez, D Camejo… - Frontiers in plant …, 2013 - frontiersin.org
Mitochondrial respiration provides the energy needed to drive metabolic and transport
processes in cells. Mitochondria are a significant site of reactive oxygen species (ROS) …

Thioredoxin-linked" thiol peroxidase" from periplasmic space of Escherichia coli

MK Cha, HK Kim, IH Kim - Journal of Biological Chemistry, 1995 - ASBMB
Three different molecular masses (24, 22, and 20 kDa) of antioxidant proteins were purified
in Escherichia coli. These proteins exhibited the preventive effects against the inactivation of …

Peroxiredoxins in parasites

MC Gretes, LB Poole, PA Karplus - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Parasite survival and virulence relies on effective defenses against reactive
oxygen and nitrogen species produced by the host immune system. Peroxiredoxins (Prxs) …

From cytoprotection to tumor suppression: the multifactorial role of peroxiredoxins

LH Butterfield, A Merino, SH Golub… - Antioxidants & redox …, 1999 - liebertpub.com
In the past decade, a new family of highly conserved antioxidant enzymes, Peroxiredoxins
(Prxs), have been discovered and defined. There are two major Prx subfamilies: one …

Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro

H Yamashita, S Avraham, S Jiang, R London… - Journal of Biological …, 1999 - ASBMB
We have isolated the cDNAs encoding human and mouse homologues of a yeast protein,
termed peroxisomal membrane protein 20 (PMP20). Comparison of the amino acid …

Antisense of human peroxiredoxin II enhances radiation-induced cell death

SH Park, YM Chung, YS Lee, HJ Kim, JS Kim… - Clinical Cancer …, 2000 - AACR
Abstract Human peroxiredoxin II (Prx II) has been known to function as an antioxidant
enzyme in cells. Using head-and-neck cancer cell lines, we investigated whether Prx II …

Induction of an antioxidant protein of Saccharomyces cerevisiae by O2, Fe3+, or 2-mercaptoethanol.

IH Kim, K Kim, SG Rhee - Proceedings of the National …, 1989 - National Acad Sciences
A soluble 27-kDa protein from Saccharomyces cerevisiae specifically prevents the
inactivation of various enzymes caused by a nonenzymatic Fe3+/O2/thiol mixed-function …

Cloning of the peroxiredoxin gene family in rats and characterization of the fourth member

A Matsumoto, A Okado, T Fujii, J Fujii, M Egashira… - FEBS …, 1999 - Wiley Online Library
Peroxiredoxin (PRx) exhibits thioredoxin‐dependent peroxidase activity and constitutes a
family of proteins. Four members of genes from rat tissues were isolated by PCR using …

IL-4 plays a crucial role in regulating oxidative damage in the liver during schistosomiasis

AC La Flamme, EA Patton, B Bauman… - The Journal of …, 2001 - journals.aai.org
Liver enlargement and hepatocyte proliferation, normal responses in wild-type (WT) mice
infected with the parasitic helminth Schistosoma mansoni, were found to be severely …

Emerging roles of thioredoxin cycle enzymes in the central nervous system

A Patenaude, MRV Murthy, ME Mirault - Cellular and Molecular Life …, 2005 - Springer
The thioredoxins (Trxs) constitute a family of enzymes which catalyze the reduction of
protein disulfide bonds. Recent animal studies have revealed the importance of the Trx …