The evolving landscape of salivary gland tumors

CE Steuer, GJ Hanna, K Viswanathan… - CA: a cancer journal …, 2023 - Wiley Online Library
Salivary gland cancers are a rare, histologically diverse group of tumors. They range from
indolent to aggressive and can cause significant morbidity and mortality. Surgical resection …

The role of molecular testing in the differential diagnosis of salivary gland carcinomas

A Skálová, G Stenman, RHW Simpson… - The American journal …, 2018 - journals.lww.com
Salivary gland neoplasms are a morphologically heterogenous group of lesions that are
often diagnostically challenging. In recent years, considerable progress in salivary gland …

Immunohistochemical analysis of salivary gland tumors: application for surgical pathology practice

T Nagao, E Sato, R Inoue, H Oshiro… - Acta histochemica et …, 2012 - jstage.jst.go.jp
© 2012 The Japan Society of Histochemistry and Salivary gland tumors are relatively
uncommon and there exists a considerable diagnostic difficulty owing to their diverse …

Androgen deprivation therapy for androgen receptor‐positive advanced salivary duct carcinoma: a nationwide case series of 35 patients in The Netherlands

E Boon, W van Boxtel, J Buter… - Head & …, 2018 - Wiley Online Library
Background Salivary duct carcinoma, an aggressive subtype of salivary gland cancer, is
mostly androgen receptor‐positive. Only limited data are available on androgen deprivation …

Review and updates of immunohistochemistry in selected salivary gland and head and neck tumors

S Zhu, C Schuerch, J Hunt - Archives of Pathology and …, 2015 - meridian.allenpress.com
Context Immunohistochemistry is a useful tool for diagnosing salivary gland and head and
neck tumors. Objective To review immunohistochemical markers, which can aid in the …

Trastuzumab for the treatment of salivary duct carcinoma

SA Limaye, MR Posner, JF Krane, M Fonfria… - The …, 2013 - academic.oup.com
Objectives. Salivary duct carcinoma (SDC) is a rare and aggressive malignancy with high
mortality and poor response to treatment. A significant fraction of SDCs are HER2 positive …

[HTML][HTML] HER2 positivity in histological subtypes of salivary gland carcinoma: a systematic review and meta-analysis

K Egebjerg, CD Harwood, NC Woller… - Frontiers in …, 2021 - frontiersin.org
Background HER2 aberrations in salivary gland carcinomas (SGC) as well as benefit of
HER2 directed therapy have been reported in small studies. However, reliable estimates of …

Salivary duct carcinoma: the predominance of apocrine morphology, prevalence of histologic variants, and androgen receptor expression

L Williams, LDR Thompson, RR Seethala… - The American journal …, 2015 - journals.lww.com
Salivary duct carcinoma (SDC) is a prototypic aggressive salivary gland carcinoma. Our aim
is to determine the prevalence of histologic variants (micropapillary, basal-like) and …

Biology and management of salivary gland cancers

DJ Adelstein, SA Koyfman, AK El-Naggar… - Seminars in radiation …, 2012 - Elsevier
The salivary gland cancers are uncommon neoplasms of the head and neck, which exhibit
considerable pathologic, biological, and clinical diversity. Surgical resection, often with …

Clinical activity of androgen deprivation therapy in patients with metastatic/relapsed androgen receptor–positive salivary gland cancers

LD Locati, F Perrone, B Cortelazzi, S Lo Vullo… - Head & …, 2016 - Wiley Online Library
Background Androgen deprivation therapy has some clinical activity in selected salivary
gland cancer histotypes, with androgen receptor expression. Methods We retrospectively …