[HTML][HTML] Standardization of bcr-abl1 p210 monitoring: From nested to digital pcr

A Jovanovski, J Petiti, E Giugliano, EM Gottardi… - Cancers, 2020 - mdpi.com
Simple Summary The diagnostic and clinical success of standardization of BCR-ABL1 p210
monitoring in chronic myeloid leukemia patients could be seen as a good example for …

[HTML][HTML] Development of molecular analyzes by digital PCR for clinical practice: positioning, current applications and perspectives

JA Denis, A Perrier, J Nectoux, PJ Lamy… - Annales de biologie …, 2019 - jle.com
[2] Didelot A., Kotsopoulos SK, Lupo A., Pekin D., Li X., Atochin I. Multiplex picoliter-droplet
digital PCR for quantitative assessment of DNA integrity in clinical samples. Clin Chem …

[HTML][HTML] Liquid biopsies and minimal residual disease in lymphoid malignancies

M Bou Zerdan, J Kassab, L Saba, E Haroun… - Frontiers in …, 2023 - frontiersin.org
Minimal residual disease (MRD) assessment using peripheral blood instead of bone marrow
aspirate/biopsy specimen or the biopsy of the cancerous infiltrated by lymphoid …

Optimal measurable residual disease testing for acute myeloid leukemia

W Xiao, K Petrova-Drus… - Surgical Pathology …, 2019 - surgpath.theclinics.com
Increasing evidence supports the prognostic significance of measurable residual disease
(MRD) in acute myeloid leukemia (AML). Dynamic MRD assessment for patients with AML …

Use of droplet digital polymerase chain reaction for detecting minimal residual disease: a prospective multi-institutional study

H Park, DY Shin, I Kim, SK Sohn, Y Koh, JH Lee… - in vivo, 2019 - iv.iiarjournals.org
Background/Aim: Droplet digital polymerase chain reaction (ddPCR) is an exact method of
measuring nucleic acids. The aim of this prospective study was to evaluate minimal residual …

[HTML][HTML] Nucleophosmin1 and isocitrate dehydrogenase 1 and 2 as measurable residual disease markers in acute myeloid leukemia

P Kövy, Z Őrfi, A Bors, A Kozma, L Gopcsa, J Dolgos… - Plos one, 2021 - journals.plos.org
Monitoring measurable residual disease (MRD) in acute myeloid leukemia (AML) plays an
important role in predicting relapse and outcome. The applicability of the leukemia-initiating …

[HTML][HTML] Advantages of digital PCR in the detection of low abundance BCR‑ABL1 gene in patients with chronic myeloid leukemia

Z Yan, Q Sun, H Zhang, Y Han, J Qiao… - Oncology …, 2019 - spandidos-publications.com
Quantitative monitoring of BCR‑ABL1IS gene using reverse transcription quantitative‑PCR
(RT‑qPCR) is an important method for evaluating the treatment effects in patients with …

[HTML][HTML] Disease Response Assessment Modalities in Chronic Myeloid Leukemia: Past, Present, and Future

DK Mishra, I Dey, R Demde, S Vinarkar… - Indian Journal of …, 2023 - thieme-connect.com
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by the BCR::
ABL1 fusion gene, which results from a reciprocal translocation between chromosome 9 and …

Transferring measurable residual disease measurement in pediatric acute lymphoblastic leukemia from quantitative real‐time PCR to digital droplet PCR

L Luib, H Kreyenberg, S Michaelis… - Pediatric …, 2023 - Wiley Online Library
Background Since the measurement of measurable residual disease (MRD) is part of
clinical routine examination for children affected with acute lymphoblastic leukemia (ALL) …

Therapeutic drug monitoring in oncology

DS Wilkinson - Therapeutic Drug Monitoring, 2019 - journals.lww.com
Historically, therapeutic drug monitoring (TDM) has mainly focused on measuring the level
of drugs and analyzing individualized pharmacokinetics. 1 However, during recent years …