Salvia miltiorrhizaBurge (Danshen): a golden herbal medicine in cardiovascular therapeutics

Z Li, S Xu, P Liu - Acta Pharmacologica Sinica, 2018 - nature.com
Abstract Salvia miltiorrhiza Burge (Danshen) is an eminent medicinal herb that possesses
broad cardiovascular and cerebrovascular protective actions and has been used in Asian …

Effects and mechanisms of compound Chinese medicine and major ingredients on microcirculatory dysfunction and organ injury induced by ischemia/reperfusion

JY Han, Q Li, ZZ Ma, JY Fan - Pharmacology & therapeutics, 2017 - Elsevier
Microcirculation dysfunction and organ injury after ischemia and reperfusion (I/R) result from
a complex pathologic process consisting of multiple links, with metabolism impairment in the …

Ferulic acid alleviates myocardial ischemia reperfusion injury via upregulating AMPKα2 expression-mediated ferroptosis depression

X Liu, K Qi, Y Gong, X Long, S Zhu, F Lu… - Journal of …, 2022 - journals.lww.com
Ferroptosis, a recently discovered form of regulated cell death that is characterized by iron
accumulation and excessive reactive oxygen species generation, has been favored by most …

[HTML][HTML] Sodium tanshinone IIA sulfonate: a review of pharmacological activity and pharmacokinetics

ZY Zhou, WR Zhao, J Zhang, XL Chen… - Biomedicine & …, 2019 - Elsevier
Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivate of tanshinone IIA (Tan IIA)
which is an active lipophilic constitute of Chinese Materia Medica Salvia miltiorrhiza …

[Retracted] A Pharmacological Review of Tanshinones, Naturally Occurring Monomers from Salvia miltiorrhiza for the Treatment of Cardiovascular Diseases

Y Yang, M Shao, W Cheng, J Yao, L Ma… - Oxidative Medicine …, 2023 - Wiley Online Library
Cardiovascular diseases (CVDs) are a set of heart and blood vessel disorders that include
coronary heart disease (CHD), rheumatic heart disease, and other conditions. Traditional …

Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury

Y Bei, LL Pan, Q Zhou, C Zhao, Y Xie, C Wu, X Meng… - BMC medicine, 2019 - Springer
Background Cathelicidins are a major group of natural antimicrobial peptides which play
essential roles in regulating host defense and immunity. In addition to the antimicrobial and …

[HTML][HTML] Pharmacological basis of tanshinone and new insights into tanshinone as a multitarget natural product for multifaceted diseases

Z Li, J Zou, D Cao, X Ma - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Drug development has long included the systematic exploration of various resources.
Among these, natural products are one of the most important resources from which novel …

Inhibition of autophagy‐dependent pyroptosis attenuates cerebral ischaemia/reperfusion injury

H Liu, Z Zhao, T Wu, Q Zhang, F Lu, J Gu… - Journal of Cellular …, 2021 - Wiley Online Library
Autophagy is closely associated with cerebral ischaemia/reperfusion injury, but the
underlying mechanisms are unknown. We investigated whether Spautin‐1 ameliorates …

Protective effects of tanshinone IIA on myocardial ischemia reperfusion injury by reducing oxidative stress, HMGB1 expression, and inflammatory reaction

H Hu, C Zhai, G Qian, A Gu, J Liu, F Ying… - Pharmaceutical …, 2015 - Taylor & Francis
Context: Although there were reports on the protective functions of tanshinone IIA (TSA) on
rat myocardial ischemia, the exerting mechanism has not been completely clarified …

[HTML][HTML] Inhibition of FOXO3a/BIM signaling pathway contributes to the protective effect of salvianolic acid A against cerebral ischemia/reperfusion injury

J Song, W Zhang, J Wang, H Yang, Q Zhou… - … Pharmaceutica Sinica B, 2019 - Elsevier
Salvianolic acid A (SalA) is an effective compound extracted from traditional Chinese
medicine Salvia miltiorrhiza Bunge. The Forkhead box O3a (FOXO3a) signaling pathway …