Flavonoids regulate tumor-associated macrophages–from structure-activity relationship to clinical potential

Q Sun, Q Liu, X Zhou, X Wang, H Li, W Zhang… - Pharmacological …, 2022 - Elsevier
In recent years, the strategy for tumor therapy has changed from focusing on the direct killing
effect of different types of therapeutic agents on cancer cells to the new mainstream of multi …

Flavonoids and cancer prevention: a review of the evidence

DF Romagnolo, OI Selmin - Journal of nutrition in gerontology and …, 2012 - Taylor & Francis
The objective of this work is to review data from epidemiological and preclinical studies
addressing the potential benefits of diets based on flavonoids for cancer prevention …

Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis

J Mishra, J Drummond, SH Quazi, SS Karanki… - Critical reviews in …, 2013 - Elsevier
Colorectal cancer is the leading cause of cancer-related mortality in the western world. It is
also the third most common cancer diagnosed in both men and women in the United States …

Polyphenols in colorectal cancer: current state of knowledge including clinical trials and molecular mechanism of action

MN Alam, M Almoyad, F Huq - BioMed research international, 2018 - Wiley Online Library
Polyphenols have been reported to have wide spectrum of biological activities including
major impact on initiation, promotion, and progression of cancer by modulating different …

Natural flavonoids for the prevention of colon cancer: A comprehensive review of preclinical and clinical studies

K Afshari, NS Haddadi, A Haj‐Mirzaian… - Journal of cellular …, 2019 - Wiley Online Library
Flavonoids comprise a group of natural polyphenols consisting of more than 5,000 subtypes
mostly existing in fruits and vegetables. Flavonoids consumption could potentially attenuate …

Microencapsulated Bifidobacterium bifidum and Lactobacillus gasseri in Combination with Quercetin Inhibit Colorectal Cancer Development in ApcMin/+ Mice

I Benito, IJ Encío, FI Milagro, M Alfaro… - International Journal of …, 2021 - mdpi.com
Recent studies have suggested that flavonoids such as quercetin and probiotics such as
Bifidobacterium bifidum (Bf) and Lactobacillus gasseri (Lg) could play a relevant role in …

Quercetin improved muscle mass and mitochondrial content in a murine model of cancer and chemotherapy-induced cachexia

BN VanderVeen, TD Cardaci, P Cunningham… - Nutrients, 2022 - mdpi.com
A cachexia diagnosis is associated with a doubling in hospital stay and increased
healthcare cost for cancer patients and most cachectic patients do not survive treatment …

Sub-chronic oral toxicity screening of quercetin in mice

P Cunningham, E Patton, BN VanderVeen… - … Medicine and Therapies, 2022 - Springer
Background Quercetin is an organic flavonoid present in several fruits and vegetables. The
anti-inflammatory, antiviral, antioxidant, cardio-protective, anti-carcinogenic and …

Immunomodulation and anti-inflammatory roles of polyphenols as anticancer agents

F Ghiringhelli, C Rebe, A Hichami… - Anti-Cancer Agents in …, 2012 - ingentaconnect.com
Cancers are the largest cause of mortality and morbidity in industrialized countries. Several
new concepts have emerged in relation to mechanisms that contribute to the regulation of …

[HTML][HTML] Sex differences in the relationship of IL-6 signaling to cancer cachexia progression

KL Hetzler, JP Hardee, MJ Puppa, AA Narsale… - … et Biophysica Acta (BBA …, 2015 - Elsevier
A devastating aspect of cancer cachexia is severe loss of muscle and fat mass. Though
cachexia occurs in both sexes, it is not well-defined in the female. The Apc Min/+ mouse is …