Hydroxytyrosol protects from aging process via AMPK and autophagy; a review of its effects on cancer, metabolic syndrome, osteoporosis, immune-mediated and …

RM De Pablos, AM Espinosa-Oliva… - Pharmacological …, 2019 - Elsevier
Aging is a complex process. It is considered a risk factor for several diseases such as
cancer, neurodegenerative diseases, cardiovascular diseases, and diabetes, most of which …

[HTML][HTML] Multiple biological functions of Twist1 in various cancers

Z Zhao, MA Rahman, ZG Chen, DM Shin - Oncotarget, 2017 - ncbi.nlm.nih.gov
Twist1 is a well-known regulator of transcription during embryonic organogenesis in many
species. In humans, Twist1 malfunction was first linked to Saethre-Chotzen syndrome and …

Physical exercise and the hallmarks of breast cancer: a narrative review

C García-Chico, S López-Ortiz, S Peñín-Grandes… - Cancers, 2023 - mdpi.com
Simple Summary The growing prevalence of breast cancer, together with the progress in
updating tumor hallmarks, increases the need to develop and investigate the molecular …

Natural compounds as modulators of cell cycle arrest: application for anticancer chemotherapies

N Bailon-Moscoso, G Cevallos-Solorzano… - Current …, 2017 - ingentaconnect.com
Natural compounds from various plants, microorganisms and marine species play an
important role in the discovery novel components that can be successfully used in numerous …

[HTML][HTML] Current status of nanomaterial-based treatment for hepatocellular carcinoma

B Baig, SA Halim, A Farrukh, Y Greish… - Biomedicine & …, 2019 - Elsevier
Cancer continues to be the leading cause of death worldwide. Hepatocellular carcinoma
(HCC), a prominent form of liver cancer, is the second leading cause of cancer-related …

Valeric acid suppresses liver cancer development by acting as a novel HDAC inhibitor

R Han, O Nusbaum, X Chen, Y Zhu - Molecular Therapy-Oncolytics, 2020 - cell.com
Liver cancer is the fastest growing cause of cancer deaths in the United States due to its
aggressiveness and lack of effective therapies. The current preclinical study examines …

Cellular mechanism of gene mutations and potential therapeutic targets in ovarian cancer

T Guo, X Dong, S Xie, L Zhang, P Zeng… - Cancer management …, 2021 - Taylor & Francis
Ovarian cancer is a common and complex malignancy with poor prognostic outcome. Most
women with ovarian cancer are diagnosed with advanced stage disease due to a lack of …

Contributions of HOX genes to cancer hallmarks: Enrichment pathway analysis and review

DB Brotto, ÁDD Siena, II de Barros… - Tumor …, 2020 - journals.sagepub.com
Homeobox genes function as master regulatory transcription factors during development,
and their expression is often altered in cancer. The HOX gene family was initially studied …

Multifactorial contribution of notch signaling in head and neck squamous cell carcinoma

C Porcheri, CT Meisel, T Mitsiadis - International journal of molecular …, 2019 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) defines a group of solid tumors
originating from the mucosa of the upper aerodigestive tract, pharynx, larynx, mouth, and …

Ursolic acid's alluring journey: one triterpenoid vs. cancer hallmarks

Y Limami, A Pinon, H Wahnou, M Oudghiri, B Liagre… - Molecules, 2023 - mdpi.com
Cancer is a multifactorial disease characterized by various hallmarks, including uncontrolled
cell growth, evasion of apoptosis, sustained angiogenesis, tissue invasion, and metastasis …