[HTML][HTML] Neuropeptide and small transmitter coexistence: fundamental studies and relevance to mental illness

T Hökfelt, S Barde, ZQD Xu, E Kuteeva… - Frontiers in neural …, 2018 - frontiersin.org
Neuropeptides are auxiliary messenger molecules that always co-exist in nerve cells with
one or more small molecule (classic) neurotransmitters. Neuropeptides act both as …

Ventral pallidum cellular and pathway specificity in drug seeking

YM Kupchik, AA Prasad - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
The ventral pallidum (VP) is central to the reinforcing effects across a variety of drugs and
relapse to drug seeking. Emerging studies from animal models of reinstatement reveal a …

Diet-induced obesity leads to alterations in behavior and gut microbiota composition in mice

REM Júnior, LM de Carvalho, DC Dos Reis… - The Journal of …, 2021 - Elsevier
The high prevalence of obesity and associated metabolic disorders are one of the major
public health problems worldwide. Among the main causal factors of obesity, excessive …

[HTML][HTML] Insight into the role of the gut-brain axis in alcohol-related responses: emphasis on GLP-1, amylin, and ghrelin

M Tufvesson-Alm, OT Shevchouk, E Jerlhag - Frontiers in Psychiatry, 2023 - frontiersin.org
Alcohol use disorder (AUD) contributes substantially to global morbidity and mortality. Given
the heterogenicity of this brain disease, available pharmacological treatments only display …

[HTML][HTML] Genetic base of behavioral disorders in mucopolysaccharidoses: transcriptomic studies

K Pierzynowska, L Gaffke, M Podlacha… - International Journal of …, 2020 - mdpi.com
Mucopolysaccharidoses (MPS) are a group of inherited metabolic diseases caused by
mutations leading to defective degradation of glycosaminoglycans (GAGs) and their …

[HTML][HTML] Galanin family peptides: Molecular structure, expression and roles in the neuroendocrine axis and in the spinal cord

S Zhu, X Hu, S Bennett, O Charlesworth… - Frontiers in …, 2022 - frontiersin.org
Galanin is a neurohormone as well as a neurotransmitter and plays versatile physiological
roles for the neuroendocrine axis, such as regulating food intake, insulin level and …

Neuropeptide receptors as potential pharmacological targets for obesity

BT Meneguetti, MH Cardoso, CFA Ribeiro… - Pharmacology & …, 2019 - Elsevier
Obesity is a chronic multifactorial disease, characterized by an excessive accumulation of
adipose tissue. It is usually the result of excessive food intake and/or low energy …

[HTML][HTML] Involvement of the dorsal vagal complex in alcohol-related behaviors

BN Keller, A Hajnal, KN Browning… - Frontiers in Behavioral …, 2022 - frontiersin.org
The neurobiological mechanisms that regulate the development and maintenance of alcohol
use disorder (AUD) are complex and involve a wide variety of within and between systems …

The ventral pallidum and relapse in alcohol seeking

AA Prasad, GP McNally - British Journal of Pharmacology, 2020 - Wiley Online Library
Alcohol‐use disorders are chronically relapsing conditions characterized by cycles of use,
abstinence and relapse. The ventral pallidum (VP) is a key node in the neural circuits …

Role of the galanin N-terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system

C Millón, A Flores-Burgess, B Gago… - Journal of …, 2019 - journals.sagepub.com
Background: Anhedonia is a core feature of depressive disorders. The galanin N-terminal
fragment (1-15) plays a role in mood regulation since it induces depression and anxiogenic …