A systematic review and individual participant data meta-analysis of gonadal steroid hormone receptors in meningioma

DF Miyagishima, V Sundaresan, AG Gutierrez… - Journal of …, 2023 - thejns.org
OBJECTIVE The relationship between patient and meningioma characteristics and hormone
receptors (HRs) of progesterone, estrogen, and androgen remains poorly defined despite …

Advances in molecular biological and translational studies in World Health Organization grades 2 and 3 meningiomas: a literature review

A Okano, S Miyawaki, Y Teranishi, K Ohara… - Neurologia medico …, 2022 - jstage.jst.go.jp
Abstract The treatment of World Health Organization (WHO) grades 2 and 3 meningiomas
remains difficult and controversial. The pathogenesis of high-grade meningiomas was …

Molecular diagnosis and treatment of meningiomas: an expert consensus (2022)

J Deng, L Hua, L Bian, H Chen, L Chen… - Chinese medical …, 2022 - journals.lww.com
Meningiomas are the most common primary intracranial neoplasm with diverse pathological
types and complicated clinical manifestations. The fifth edition of the WHO Classification of …

Obesity and meningioma: a US population-based study paired with analysis of a multi-institutional cohort

R Khazanchi, KR Nandoliya, MN Shahin, AI Rae… - Journal of …, 2024 - thejns.org
OBJECTIVE Whether obesity is associated with meningioma and the impact of obesity by
gender has been debated. The primary objective of this study was to investigate differences …

Meningioma: International Consortium on Meningiomas (ICOM) consensus review on scientific advances & treatment paradigms for clinicians, researchers, and …

JZ Wang, AP Landry, DR Raleigh, F Sahm… - Neuro …, 2024 - academic.oup.com
Meningiomas are the most common primary intracranial tumors in adults and are increasing
in incidence due to the aging population and the rising availability of neuroimaging. While …

Novel medical therapies in meningiomas

H Danish, P Brastianos - Biological and Clinical Landscape of …, 2023 - Springer
Meningiomas are the most common primary brain tumor in adults and have been historically
managed with surgery and radiation therapy. However, in patients with inoperable, recurrent …

The role of progesterone and the progesterone receptor in cancer

JH Check - Expert review of endocrinology & metabolism, 2017 - Taylor & Francis
Introduction: There is an abundance of accumulating data strongly suggesting there is a key
role for the progesterone receptor in the molecular events effecting the growth or …

Brain-invasive meningiomas: molecular mechanisms and potential therapeutic options

C Qin, M Huang, Y Pan, Y Li, W Long, Q Liu - Brain Tumor Pathology, 2021 - Springer
Meningiomas are the most commonly diagnosed benign intracranial adult tumors. Subsets
of meningiomas that present with extensive invasion into surrounding brain areas have high …

New insights as to why progesterone receptor modulators, such as mifepristone, seem to be more effective in treating cancers that are devoid of the classical nuclear …

JH Check, D Check - Anticancer Research, 2021 - ar.iiarjournals.org
Mifepristone treatment for advanced cancer has demonstrated considerable improvement in
both length and quality of life in patients who no longer have any other treatment options …

Bevacizumab in refractory higher-grade and atypical meningioma: the current state of affairs

CA Dasanu, J Alvarez-Argote… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Historically, systemic agents had shown limited efficacy in meningioma, at the
expense of significant pharmacologic and/or financial toxicity. As meningiomas are highly …