[HTML][HTML] A review on exosomes application in clinical trials: Perspective, questions, and challenges

J Rezaie, M Feghhi, T Etemadi - Cell …, 2022 - biosignaling.biomedcentral.com
Exosomes are progressively known as significant mediators of cell-to-cell communication.
They convey active biomolecules to target cells and have vital functions in several …

[HTML][HTML] Exosome-based vaccines: history, current state, and clinical trials

P Santos, F Almeida - Frontiers in Immunology, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by most cell types as part of an intracellular
communication system in crucial processes such as inflammation, cell proliferation, and …

[HTML][HTML] The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy

J Li, G Zhang, CG Liu, X Xiang, MTN Le, G Sethi… - Theranostics, 2022 - ncbi.nlm.nih.gov
Exosomes are multifunctional regulators of intercellular communication by carrying various
messages under both physiological and pathological status of cancer patients …

Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment

Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

[HTML][HTML] Universal immunotherapeutic strategy for hepatocellular carcinoma with exosome vaccines that engage adaptive and innate immune responses

B Zuo, Y Zhang, K Zhao, L Wu… - … of Hematology & …, 2022 - jhoonline.biomedcentral.com
Personalized immunotherapy utilizing cancer vaccines tailored to the tumors of individual
patients holds promise for tumors with high genetic heterogeneity, potentially enabling …

Extracellular vesicles as delivery systems at nano-/micro-scale

P Fu, J Zhang, H Li, M Mak, W Xu, Z Tao - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) have shown significant promises as nano-/micro-size carriers in
drug delivery and bioimaging. With more characteristics of EVs explored through …

[HTML][HTML] The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer

X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & Molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …

[HTML][HTML] Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy

X Han, A Alu, H Liu, Y Shi, X Wei, L Cai, Y Wei - Bioactive Materials, 2022 - Elsevier
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …

Scalable production of extracellular vesicles and its therapeutic values: a review

CY Ng, LT Kee, ME Al-Masawa, QH Lee… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …

[HTML][HTML] Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment

A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), is the umbrella term used for different types of vesicles
produced by the cells, among which exosomes form the largest group. Exosomes perform …