Abstract Background Many antiepileptic drugs (AEDs) have the potential to cause
teratogenicity. We evaluated eight antiepileptic drugs (AEDs) classified as Federal Drug …

Epilepsy is one of the few neurologic disorders that requires a constant treatment during
pregnancy. Epilepsy affects 0.3-0.8% of pregnant women. Prescription of antiepileptic drugs …

Background: Evidence from developed countries demonstrates that the use of antiseizure
medications (ASMs) has been increasing in the last decade. Pregnant women have a very …

Carbamazepine (CBZ) is an anticonvulsant drug used for epilepsy and other disorders.
Prescription of CBZ during pregnancy increases the risk for congenital malformations. CBZ …

Differentiating pluripotent stem cells in vitro have proven useful for the study of
developmental toxicity. Here, we studied the effects of anticonvulsant drug exposure in a …

Valproic acid or valproate (VPA) is an anti-convulsant and mood stabiliser effective in
treating epilepsy and bipolar disorders. Although in adults VPA is well tolerated and safe …

Epilepsy affects approximately 1% of children under the age of 15, making it a very common
neurological disorder in the pediatric population (Russ et al., 2012 [1]). In addition,~ 0.4 …

Purpose/Background High risks of neural tube defects and other teratogenic effects are
associated with exposure in early pregnancy to some anticonvulsants, including in women …

Purpose To determine the prevalence and predictors of folic acid (FA) use by women with
epilepsy (WWE) at risk of unintended pregnancy. Methods These retrospective data come …

BACKGROUND: Treatment of paediatric epilepsy has advanced with the development of
new antiepileptic drugs (AEDs). There are few data for Germany to which extent new AEDs …