Background Maternal folic acid (FA) intake before and during early pregnancy reduces the
risk for neural tube defects (NTDs); evidence suggests it may also reduce the risk for oral …

Background: In the recent past, many third-generation antiepileptic drugs (AEDs) including
Pregabalin (PGB) were launched for the treatment of diverse forms of epilepsy with better …

Purpose To evaluate fetal or neonatal outcomes (with a focus on major congenital
anomalies) with use of topiramate monotherapy and to examine whether differences …

The skull and appendicular bones are derived from different embryological sources during
their development. The impact of prenatal exposure of topiramate on ossification of these …

Carbamazepine (CBZ) is one of the most widely used antiepileptic drugs by both adults and
children. Despite its widespread use, CBZ is associated with central nervous system toxicity …

Риски, связанные с внутриутробным влиянием противоэпилептических препаратов
(ПЭП), имеют большое значение как для женщин, страдающих эпилепсией, так и для …

The histoqualitative teratogenic effects of lamotrigine, a second-line anticonvulsant
medicine, on the developing fetal brain structures when exposed in utero in a time-and dose …

Background SCN8A mutations are rare and cause a phenotypically heterogeneous early
onset epilepsy known as early infantile epileptic encephalopathy type 13 (EIEE13, OMIM# …

(1) Background: The utilization of high-quality evidence regarding the safety of anti-seizure
medications (ASMs) is constrained by the absence of standardized reporting. This study …

Aminobutyrate aminotransferase (GABA) receptors are the key mediators of quick inhibitory
synaptic transmission in the midpoint of the nervous system in mammalian. Dysfunction of …