This study reports the comparative molecular modeling, docking and dynamic simulations of
human α9α10 nicotinic acetylcholine receptors complexed with acetylcholine, nicotine and α …

Quercetin, one of the flavonoids, is a low molecular weight substance found in fruits and
vegetables. Quercetin, like other flavonoids, has a wide range of neuropharmacological …

Publisher Summary The nicotinic acetylcholine receptors (nAChRs) are a family of cationic
ligand–gated ion channels and are members of the cys-loop receptor superfamily. The α7 …

The expression and function of nicotinic receptor subunits (nAChRs) in the inner ear before
the onset of hearing is not well understood. We investigated the mRNA expression of the α9 …

Ionotropic receptors mediate rapid communication between neurons. These receptors are
oligomers and are usually assembled from multiple subunit types. Receptors built from …

Nicotinic acetylcholine receptors (nAChRs) are highly conserved between humans and non-
human primates. Conservation exists at the level of genomic structure, protein structure and …

Neurons of the medial olivary complex inhibit cochlear hair cells through the activation of
α9α10-containing nicotinic acetylcholine receptors (nAChRs). Efforts to study the localization …

Cholinergic transmission is essential for survival and reproduction, as it is involved in
several physiological responses. In the auditory system, both ascending and descending …

In the mature mammalian auditory system, inner hair cells are responsible for converting
sound-evoked vibrations into graded electrical responses, resulting in release of …

It was reported that nicotinic acetylcholine receptor (nAChR)-mediated signaling pathways
affect the proliferation and differentiation of pluripotent stem cells. However, detail …