Muscle insulin resistance: assault by lipids, cytokines and local macrophages

G Kewalramani, PJ Bilan, A Klip - Current Opinion in Clinical …, 2010 - journals.lww.com
Altered intramuscular lipid metabolism, circulating cytokines, and inflammatory macrophage
infiltration of muscle tissue have been recently linked to muscle insulin resistance provoked …

Polyunsaturated fatty acids: from diet to binding to ppars and other nuclear receptors

A Bordoni, M Di Nunzio, F Danesi, PL Biagi - Genes & nutrition, 2006 - Springer
Dietary polyunsaturated fatty acids (PUFAs) function not only by altering membrane lipid
composition, cellular metabolism, signal transduction, but possess also effects on gene …

Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training

S Schenk, JF Horowitz - American Journal of Physiology …, 2006 - journals.physiology.org
Although the increase in fatty acid oxidation after endurance exercise training has been
linked with improvements in insulin sensitivity and overall metabolic health, the mechanisms …

High dietary fat intake increases fat oxidation and reduces skeletal muscle mitochondrial respiration in trained humans.

JJ Leckey, NJ Hoffman, EB Parr… - The FASEB …, 2018 - researchonline.ljmu.ac.uk
High-fat, low-carbohydrate (CHO) diets increase whole-body rates of fat oxidation and down-
regulate CHO metabolism. We measured substrate utilization and skeletal muscle …

Effect of exercise training on metabolic flexibility in response to a high-fat diet in obese individuals

GM Battaglia, D Zheng, RC Hickner… - American Journal of …, 2012 - journals.physiology.org
Obese individuals typically exhibit a reduced capacity for metabolic flexibility by failing to
increase fatty acid oxidation (FAO) upon the imposition of a high-fat diet (HFD). Exercise …

Fat and carbohydrate metabolism during submaximal exercise in children

J Aucouturier, JS Baker, P Duché - Sports Medicine, 2008 - Springer
During exercise, the contribution of fat and carbohydrate to energy expenditure is largely
modulated by the intensity of exercise. Age, a short-or long-term diet enriched in …

[HTML][HTML] Metabolic Effects of Ketogenic Diets: Exploring Whole-Body Metabolism in Connection with Adipose Tissue and Other Metabolic Organs

Y Ahmad, DS Seo, Y Jang - International Journal of Molecular Sciences, 2024 - mdpi.com
The ketogenic diet (KD) is characterized by minimal carbohydrate, moderate protein, and
high fat intake, leading to ketosis. It is recognized for its efficiency in weight loss, metabolic …

Fat adaptation followed by carbohydrate restoration increases AMPK activity in skeletal muscle from trained humans

WK Yeo, SJ Lessard, ZP Chen… - Journal of applied …, 2008 - journals.physiology.org
We have previously reported that 5 days of a high-fat diet followed by 1 day of high-
carbohydrate intake (Fat-adapt) increased rates of fat oxidation and decreased rates of …

Intramyocellular lipid content and molecular adaptations in response to a 1‐week high‐fat diet

VB Schrauwen‐Hinderling, ME Kooi… - Obesity …, 2005 - Wiley Online Library
Objective: To investigate molecular adaptations that accompany the elevation of
intramyocellular lipid (IMCL) content on a high‐fat (HF) diet for 1 week. Research Methods …

[HTML][HTML] Association between “cluster of differentiation 36 (CD36)” and adipose tissue lipolysis during exercise training: A systematic review

EM El Ouali, L Bosquet, B Elgharbaoui, F Laziri… - Frontiers in …, 2023 - frontiersin.org
Fatty acid translocase (FAT/CD36) is a transmembrane glycoprotein belonging to the
scavenger class B receptor family and is encoded by the cluster of differentiation 36 (CD36) …