Probing the drug delivery strategies in ischemic stroke therapy
Q Wu, R Yan, J Sun - Drug Delivery, 2020 - Taylor & Francis
Ischemic stroke, which is caused by a sudden clot in the blood vessels, may cause severe
brain tissue damage and has become a leading cause of death globally. Currently …
brain tissue damage and has become a leading cause of death globally. Currently …
Malignancy‐associated ischemic stroke: Implications for diagnostic and therapeutic workup
W Xie, S Hsu, Y Lin, L Xie, X Jin, Z Zhu… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Patients with malignancies have an increased risk of suffering ischemic stroke
via several mechanisms such as coagulation dysfunction and other malignancy‐related …
via several mechanisms such as coagulation dysfunction and other malignancy‐related …
Neuroprotective efficacy of an aminopropyl carbazole derivative P7C3‐A20 in ischemic stroke
SN Wang, TY Xu, X Wang, YF Guan… - CNS neuroscience & …, 2016 - Wiley Online Library
Aim NAMPT is a novel therapeutic target of ischemic stroke. The aim of this study was to
investigate the effect of a potential NAMPT activator, P7C3‐A20, an aminopropyl carbazole …
investigate the effect of a potential NAMPT activator, P7C3‐A20, an aminopropyl carbazole …
Population pharmacokinetic‐pharmacodynamic modeling of clopidogrel for dose regimen optimization based on CYP2C19 phenotypes: A proof of concept study
YS Jung, BH Jin, MS Park, CO Kim… - CPT: Pharmacometrics …, 2024 - Wiley Online Library
Clopidogrel is an antiplatelet drug used to reduce the risk of acute coronary syndrome and
stroke. It is converted by CYP2C19 to its active metabolite; therefore, poor metabolizers …
stroke. It is converted by CYP2C19 to its active metabolite; therefore, poor metabolizers …
Efficacy and Safety of Anticoagulant Therapy Versus Antiplatelet Therapy in Acute Ischemic Stroke Patients with Atrial Fibrillation
X Yan, B Wang, P Xia, C Lan, Q Wang… - Clinical and Applied …, 2023 - journals.sagepub.com
The efficacy and safety of anticoagulant therapy in patients with acute ischemic stroke (AIS)
and atrial fibrillation (AF) remain uncertain. This study enrolled 431 AIS and AF patients from …
and atrial fibrillation (AF) remain uncertain. This study enrolled 431 AIS and AF patients from …
Predictors of intracranial cerebral artery stenosis in patients before cardiac surgery and its impact on perioperative and long-term stroke risk
P Luchowski, J Wojczal, K Buraczynska… - Neurologia i …, 2015 - journals.viamedica.pl
Background The aim of this prospective study was to determine the prevalence of stenosis
within intracranial and extracranial arteries in patients before coronary artery bypass surgery …
within intracranial and extracranial arteries in patients before coronary artery bypass surgery …
[HTML][HTML] High triglyceride is an independent predictor of high on-treatment platelet reactivity in ischemic stroke patients
H Chen, Y Zhan, Z Lou, H Mao, C Zhang, X Li… - Journal of Stroke and …, 2022 - Elsevier
Background Previous studies have shown high triglyceride (TG) is associated with platelet
hyperactivation in metabolic syndrome patients. However, limited information is available …
hyperactivation in metabolic syndrome patients. However, limited information is available …
[HTML][HTML] Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat
H Kumar, A Boini, M Tshibangu, B Ghosh, F Shaheen… - Cureus, 2023 - ncbi.nlm.nih.gov
Anticoagulation therapy is critical to avoiding thrombotic events in patients following cranial
surgery. Although Aspirin, Plavix, and Aggrastat are used as anticoagulants for this purpose …
surgery. Although Aspirin, Plavix, and Aggrastat are used as anticoagulants for this purpose …
Direct Determination of Enzymes in Dried Blood Spots by High-Performance Liquid Chromatography–Mass Spectrometry (HPLC-MS) for the Screening of …
R Li, X Zou, P Luan, X Liu, N Wang, Q Wang… - Analytical …, 2022 - Taylor & Francis
Thrombosis is the main cause of many cardiovascular diseases. The conventional
pharmaceuticals used for preventing thrombosis can induce significant adverse side effects …
pharmaceuticals used for preventing thrombosis can induce significant adverse side effects …
Novel platelet glycoprotein VI and CLEC-2 targeting strategies: studies in humanized mouse models
S Navarro - 2023 - cris.maastrichtuniversity.nl
Drugs targeting platelets play an important role in preventing or treating thrombotic events,
for example stroke and heart attack, thus increasing the life quality and expectancy of …
for example stroke and heart attack, thus increasing the life quality and expectancy of …