Pathogenesis II: fungal responses to host responses: interaction of host cells with fungi

MJS Mendes-Giannini, ML Taylor, JB Bouchara… - Medical …, 2000 - Taylor & Francis
Most of our knowledge concerning the virulence determinants of pathogenic fungicomes
from the infected host, mainly from animal models and more recently from in vitro studies …

FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection

SC Kerr, GJ Fischer, M Sinha, O McCabe… - PLoS …, 2016 - journals.plos.org
The immune mechanisms that recognize inhaled Aspergillus fumigatus conidia to promote
their elimination from the lungs are incompletely understood. FleA is a lectin expressed by …

How environmental fungi cause a range of clinical outcomes in susceptible hosts

ST Denham, MA Wambaugh, JCS Brown - Journal of molecular biology, 2019 - Elsevier
Environmental fungi are globally ubiquitous and human exposure is near universal.
However, relatively few fungal species are capable of infecting humans, and among fungi …

[HTML][HTML] Basement membranes in obstructive pulmonary diseases

BGJ Dekkers, SI Saad, LJ van Spelde, JK Burgess - Matrix biology plus, 2021 - Elsevier
Increased and changed deposition of extracellular matrix proteins is a key feature of airway
wall remodeling in obstructive pulmonary diseases, including asthma and chronic …

Many faces of pulmonary aspergillosis

OP Sharma, R Chwogule - European Respiratory Journal, 1998 - Eur Respiratory Soc
Aspergillus is a ubiquitous fungus. It is commonly isolated as an upper respiratory tract
saprophyte and is the most frequent contaminant in laboratory specimens. Because species …

Interaction of pathogenic fungi with host cells: Molecular and cellular approaches

MJS Mendes-Giannini, CP Soares… - FEMS Immunology & …, 2005 - academic.oup.com
This review provides an overview of several molecular and cellular approaches that are
likely to supply insights into the host-fungus interaction. Fungi present intra-and/or …

[HTML][HTML] Binding of extracellular matrix proteins to Paracoccidioides brasiliensis

MJS Mendes-Giannini, PF Andreotti, LR Vincenzi… - Microbes and …, 2006 - Elsevier
Adhesion to extracellular matrix (ECM) proteins plays a crucial role in invasive fungal
diseases. ECM proteins bind to the surface of Paracoccidioides brasiliensis yeast cells in …

Identification and characterization of a laminin-binding protein of Aspergillus fumigatus: extracellular thaumatin domain protein (AfCalAp)

SK Upadhyay, L Mahajan, S Ramjee… - Journal of medical …, 2009 - microbiologyresearch.org
Aspergillus fumigatus, an opportunistic fungal pathogen, infects the human host via
inhalation of airborne conidia. Adhesion of fungal conidia, to host cells and extracellular …

Pulmonary host defences against Aspergillus fumigatus

E Roilides, H Katsifa, TJ Walsh - Research in immunology, 1998 - Elsevier
Due to expansion of the population of itnmuno-compromised hosts and intensification of
medical treatments during the last three decades, the fre-quency of opportunistic fungal …

Invasive pulmonary aspergillosis in hospital and ventilator-associated pneumonias

F Chen, D Qasir, AC Morris - Seminars in respiratory and …, 2022 - thieme-connect.com
Pneumonia is the commonest nosocomial infection complicating hospital stay, with both non-
ventilated hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) …