current concepts in inflammatory skin diseases evolved by transcriptome analysis: In-depth analysis of atopic dermatitis and psoriasis

J Schwingen, M Kaplan, FC Kurschus - International journal of molecular …, 2020 - mdpi.com
During the last decades, high-throughput assessment of gene expression in patient tissues
using microarray technology or RNA-Seq took center stage in clinical research. Insights into …

Ah receptor pathway intricacies; signaling through diverse protein partners and DNA-motifs

DP Jackson, AD Joshi, CJ Elferink - Toxicology research, 2015 - pubs.rsc.org
Ah receptor pathway intricacies; signaling through diverse protein partners and DNA-motifs -
Toxicology Research (RSC Publishing) DOI:10.1039/C4TX00236A Royal Society of …

[HTML][HTML] Molecular and morphological characterization of inflammatory infiltrate in rosacea reveals activation of Th1/Th17 pathways

T Buhl, M Sulk, P Nowak, J Buddenkotte… - Journal of Investigative …, 2015 - Elsevier
Rosacea is a common chronic inflammatory skin disease of unknown etiology. Our
knowledge about an involvement of the adaptive immune system is very limited. We …

Exploration of candidate biomarkers for human psoriasis based on gas chromatography‐mass spectrometry serum metabolomics

H Kang, X Li, Q Zhou, C Quan, F Xue… - British Journal of …, 2017 - academic.oup.com
Background Recent studies have shown that dysregulated metabolic pathways are linked to
psoriasis pathogenesis. However, an extensive, unbiased metabolic analysis in patients …

Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation

YL Chen, JSW Ng, R Ottakandathil Babu, J Woo… - Science …, 2023 - science.org
Group A Streptococcus (GAS) infection is associated with multiple clinical sequelae,
including different subtypes of psoriasis. Such post-streptococcal disorders have been long …

Network analysis of psoriasis reveals biological pathways and roles for coding and long non-coding RNAs

R Ahn, R Gupta, K Lai, N Chopra, ST Arron, W Liao - BMC genomics, 2016 - Springer
Background Psoriasis is an immune-mediated, inflammatory disorder of the skin
characterized by chronic inflammation and hyperproliferation of the epidermis. Differential …

[HTML][HTML] Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis

AW Armstrong, J Wu, MA Johnson, D Grapov… - …, 2014 - ncbi.nlm.nih.gov
Importance: While “omics” studies have advanced our understanding of inflammatory skin
diseases, metabolomics is mostly an unexplored field in dermatology. Objective: We sought …

Decreased expression of miR‐204‐3p in peripheral blood and wound margin tissue associated with the onset and poor wound healing of diabetic foot ulcers

X Zhao, M Xu, Y Tang, D Xie, L Deng… - International Wound …, 2023 - Wiley Online Library
To investigate the relationship between small non‐coding RNA‐204‐3p (miR‐204‐3p) and
the onset and wound healing of diabetic foot ulcers (DFU) and the underlying molecular …

Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression

GD Kim, R Das, L Goduni, S McClellan… - Journal of Biological …, 2016 - ASBMB
Macrophages are the predominant innate immune cells recruited to tissues following injury
or infection. These early-responding, pro-inflammatory macrophages play an essential role …

Topical ivermectin 10 mg/g and oral doxycycline 40 mg modified-release: current evidence on the complementary use of anti-inflammatory rosacea treatments

M Steinhoff, M Vocanson, JJ Voegel… - Advances in …, 2016 - Springer
Rosacea is a common, chronic inflammatory skin disease that can present with a variety of
signs and symptoms. The potentially simultaneous occurrence of different signs and …