Urine provides an alternative to blood plasma as a potential source of disease biomarkers.
One urinary biomarker already exploited in clinical studies is aquaporin-2. However, it …

Acute kidney injury (AKI), previously referred to as acute renal failure, represents a common
and devastating problem in clinical medicine. Despite significant improvements in …

Abstract Chronic Kidney Disease (CKD) is a global health problem annually affecting
millions of people around the world. It is a comprehensive syndrome, and various factors …

Diagnosis of the type of glomerular disease that causes the nephrotic syndrome is
necessary for appropriate treatment and typically requires a renal biopsy. The goal of this …

Aims: The lack of early biomarkers for acute renal failure (ARF) has crippled our ability to
launch potentially effective therapeutic measures. We tested the hypothesis that urinary …

Background Currently, early diagnosis of diabetic nephropathy (DN) remains a major
challenge. Thus, more investigations into new DN‐related biomarkers are needed. Methods …

Protein measurement in urine has been used for many years for the diagnosis and
monitoring of renal disease. The pattern of urinary protein excretion can be used to identify …

The aim of the present study was to develop a LC-MS/MS-based proteomic analysis method
of urinary exosomal proteins that has the potential to discover disease biomarkers. In short …

Increasing attention has been paid to the urinary proteome because it holds the promise of
discovering various disease biomarkers. However, most of the urine proteomics studies …

Identification and characterization of biomarkers in body fluids such as serum or urine serve
as a basis for early detection of diseases, particularly of cancer. Performing 2‐DE with …