Molecular targeted therapy for anticancer treatment

HY Min, HY Lee - Experimental & molecular medicine, 2022 - nature.com
Since the initial clinical approval in the late 1990s and remarkable anticancer effects for
certain types of cancer, molecular targeted therapy utilizing small molecule agents or …

Exosomes in angiogenesis and anti-angiogenic therapy in cancers

W Olejarz, G Kubiak-Tomaszewska… - International journal of …, 2020 - mdpi.com
Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …

[HTML][HTML] Resistance mechanisms to anti-angiogenic therapies in cancer

Y Haibe, M Kreidieh, H El Hajj, I Khalifeh… - Frontiers in …, 2020 - frontiersin.org
Tumor growth and metastasis rely on tumor vascular network for the adequate supply of
oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth …

The role of angiogenesis in cancer treatment

M Rajabi, SA Mousa - Biomedicines, 2017 - mdpi.com
A number of anti-angiogenesis drugs have been FDA-approved and are being used in
cancer treatment, and a number of other agents are in different stages of clinical …

Nanotechnology for angiogenesis: opportunities and challenges

S Kargozar, F Baino, S Hamzehlou… - Chemical Society …, 2020 - pubs.rsc.org
Angiogenesis plays a critical role within the human body, from the early stages of life (ie,
embryonic development) to life-threatening diseases (eg, cancer, heart attack, stroke, wound …

Recent discoveries of anticancer flavonoids

D Raffa, B Maggio, MV Raimondi, F Plescia… - European journal of …, 2017 - Elsevier
In this review we report the recent advances in anticancer activity of the family of natural
occurring flavonoids, covering the time span of the last five years. The bibliographic data will …

Pathological and molecular features of glioblastoma and its peritumoral tissue

A D'Alessio, G Proietti, G Sica, BM Scicchitano - Cancers, 2019 - mdpi.com
Glioblastoma (GBM) is one of the most aggressive and lethal human brain tumors. At
present, GBMs are divided in primary and secondary on the basis of the mutational status of …

[HTML][HTML] Targeting angiogenesis in breast cancer: current evidence and future perspectives of novel anti-angiogenic approaches

NM Ayoub, SK Jaradat, KM Al-Shami… - Frontiers in …, 2022 - frontiersin.org
Angiogenesis is a vital process for the growth and dissemination of solid cancers. Numerous
molecular pathways are known to drive angiogenic switch in cancer cells promoting the …

Molecular characteristics, clinical significance, and cancer immune interactions of angiogenesis-associated genes in gastric cancer

X Qing, W Xu, S Liu, Z Chen, C Ye… - Frontiers in immunology, 2022 - frontiersin.org
Background Immunotherapy has evolved as a critical option to treat diverse cancers. The
active response to immunotherapy relies on the unique interaction between cancer and the …

New angiogenic regulators produced by TAMs: perspective for targeting tumor angiogenesis

I Larionova, E Kazakova, T Gerashchenko… - Cancers, 2021 - mdpi.com
Simple Summary Since the targeting of a single pro-angiogenic factor fails to improve
oncological disease outcome, significant efforts have been made to identify new pro …