Neuroimaging and neurophysiological studies have shown that nociceptive stimuli elicit
responses in an extensive cortical network including somatosensory, insular and cingulate …

Pain diagnosis and management would benefit from the development of objective markers
of nociception and pain. Current research addressing this issue has focused on five main …

Abstract Background Cut-off points (CPs) of the numeric rating scale (NRS 0–10) are
regularly used in postoperative pain treatment. However, there is insufficient evidence to …

Although general anaesthesia has been of tremendous importance for the development of
surgery, the underlying mechanisms by which this state is achieved are only just beginning …

A meta‐analysis of 140 neuroimaging studies was performed using the activation‐likelihood‐
estimate (ALE) method to explore the location and extent of activation in the brain in …

Several studies in cognitive neuroscience have investigated the cognitive and affective
modulation of pain. By contrast, fewer studies have focused on the social modulation of pain …

The cerebellum is classically considered to be a brain region involved in motor processing,
but it has also been implicated in non-motor, and even cognitive, functions. Though previous …

Background Patients in a minimally conscious state (MCS) show restricted self or
environment awareness but are unable to communicate consistently and reliably. Therefore …

Since the advent of modern neuroimaging techniques, studies have been carried out to
examine nociceptive processing within the human brain non-invasively. Combined with …

Rationale: Dyspnea is a traumatic experience. Only limited information is available on
dyspnea in intubated critically ill patients. Objectives: Our objectives were 1) to quantify the …