Epstein–Barr virus (EBV) infection contributes to the development of several different types
of human malignancy, including Burkitt lymphoma, Hodgkin lymphoma, and …

Early growth response 1 (EGR1) is a multifunctional mammalian transcription factor capable
of both enhancing and/or inhibiting gene expression. EGR1 can be activated by a wide array …

Bacterial meningitis remains a leading cause of infection-related mortality worldwide.
Although Escherichia coli (E. coli) is the most common etiology of neonatal meningitis, the …

Viruses are obligate intracellular parasites, relying to a major extent on the host cell for
replication. An active replication of the viral genome results in a lytic infection characterized …

Viruses rely on the host translation machinery to complete their life cycles. Picornaviruses
use an internal ribosome entry site to initiate cap-independent protein translation and in …

Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …

Scleroderma (SSc) is a complex and heterogeneous connective tissue disease mainly
characterized by autoimmunity, vascular damage, and fibrosis that mostly involve the skin …

Epstein-Barr virus (EBV) has been associated with several types of human cancers. In the
host, EBV can establish two alternative modes of life cycle, known as latent or lytic and the …

Understanding factors that affect the infectivity of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is central to combatting coronavirus disease 2019 (COVID-19) …

When cellular reducing enzymes fail to shield the cell from increased amounts of reactive
oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and …