The medicinal plant Scutellaria baicalensis, commonly known as Chinese skullcap or
Huang‐Qin, has been used as a traditional medicine for several thousand years. The roots …

Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

Utilizing T cells expressing chimeric antigen receptors (CARs) to identify and attack solid
tumors has proven challenging, in large part because of the lack of tumor-specific targets to …

Ischemic stroke is an acute and severe neurological disease with high mortality and
disability rates worldwide. Polymerase I and transcript release factor (PTRF) plays a pivotal …

Paclitaxel is a natural anticancer compound with minimal toxicity, the capacity to stabilize
microtubules, and high efficiency that has remained the standard of treatment alongside …

Epithelial ovarian cancer (EOC) is the most lethal of all gynecologic malignancies. Despite
advances in surgical and chemotherapeutic options, most patients with advanced EOC have …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignant disease with a 5-
year survival rate of< 10%. Aberrant activation or elevated expression of the tyrosine kinase …

Ovarian cancer (OC) is one of the most common types of cancer in women with a high
mortality rate, and the treatment of OC is prone to high recurrence rates and side effects …

Hypoxia, a common factor ruling the microenvironment composition, leads to tumor
progression. In this hypoxic context, cytokines and cells cooperate to favor cancer …

Tamoxifen (TAM) resistance has indicated a significant challenge during endocrine therapy
for hormone-sensitive breast cancer. Thus, it is significant to elucidate the molecular events …