Peroxisome proliferator activated receptor alpha (PPAR-α) belongs to the family of ligand-
regulated nuclear receptors (PPARs). These receptors after heterodimerization with retinoid …

Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors
including PPARα, PPARγ, and PPARβ/δ, acting as transcription factors to regulate the …

The increased legal availability of cannabis has led to a common misconception that it is a
safe natural remedy for, among others, pregnancy-related ailments such as morning …

The existence of acylethanolamides (AEs) in the mammalian brain has been known for
decades. Among AEs, palmitoylethanolamide (PEA) is abundant in the central nervous …

Nicotine stimulates brain reward circuitries, most prominently the mesocorticolimbic
dopamine system, and this action plays a critical in establishing and maintaining the tobacco …

Background Per-and polyfluoroalkyl substances (PFASs) are suspected developmental
toxicants, but epidemiological evidence on neurodevelopmental effects of PFAS exposure is …

Signalling lipids are known to control a wide array of cellular processes, including cell
proliferation, apoptosis, migration, and energy metabolism. Fatty acids and their derivatives …

Midbrain dopamine (DA) neurons play a central role in a wide range of behaviors, from
attention and motivation to motor control and reinforcement. The release of DA is modulated …

Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with two major
behavioral symptoms ie repetitive behavior and social-communication impairment. The …

Tobacco use disorder is a chronic illness. With its high comorbidity rate, it is a major cause of
years of life lost or years lived with disability; however, it is also considered the most …