[HTML][HTML] Cholera toxin B: one subunit with many pharmaceutical applications

KJ Baldauf, JM Royal, KT Hamorsky, N Matoba - Toxins, 2015 - mdpi.com
Cholera, a waterborne acute diarrheal disease caused by Vibrio cholerae, remains
prevalent in underdeveloped countries and is a serious health threat to those living in …

Vaccine development against Helicobacter pylori: from ideal antigens to the current landscape

I Dos Santos Viana, ML Cordeiro Santos… - Expert review of …, 2021 - Taylor & Francis
Introduction: The interest of the world scientific community for an effective vaccine against
Helicobacter pylori infection arises from its high prevalence and association with many …

Oral Helicobacter pylori vaccine-encapsulated acid-resistant HP55/PLGA nanoparticles promote immune protection

Z Tan, W Liu, H Liu, C Li, Y Zhang, X Meng… - European Journal of …, 2017 - Elsevier
Oral vaccination, is notoriously weak or nonimmunogenic. One of the major reasons is the
inefficient antigen uptake caused by enzymolysis and hydrolysis in the gastrointestinal tract …

Helicobacter urease suppresses cytotoxic CD8+ T-cell responses through activating Myh9-dependent induction of PD-L1

J Wu, X Zhu, X Guo, Z Yang, Q Cai, D Gu… - International …, 2021 - academic.oup.com
As a key virulence factor for persistent colonization, urease B subunit (UreB) is considered to
be an ideal vaccine antigen against Helicobacter pylori infection. However, the role and …

A comprehensive evaluation of an animal model for Helicobacter pylori‐associated stomach cancer: Fact and controversy

R Amalia, NSR Panenggak, D Doohan… - …, 2023 - Wiley Online Library
Even though Helicobacter pylori infection was the most causative factor of gastric cancer,
numerous in vivo studies failed to induce gastric cancer using H. pylori infection only. The …

Oral multivalent epitope vaccine, based on UreB, HpaA, CAT, and LTB, for prevention and treatment of Helicobacter pylori infection in C57BL / 6 mice

W Xie, W Zhao, Z Zou, L Kong, L Yang - Helicobacter, 2021 - Wiley Online Library
Background As the resistance of Helicobacter pylori to traditional triple therapy is gradually
revealed, an increasing number of people are focusing on vaccine treatments for H. pylori …

[HTML][HTML] A Short Peptide of Autotransporter Ata Is a Promising Protective Antigen for Vaccination Against Acinetobacter baumannii

P Sun, X Li, C Pan, Z Liu, J Wu, H Wang… - Frontiers in …, 2022 - frontiersin.org
With the emergence of multidrug-resistant strains, Acinetobacter baumannii infection is
becoming a thorny health problem in hospitals. However, there are no licensed vaccines …

[HTML][HTML] Construction of orthogonal modular proteinaceous nanovaccine delivery vectors based on mSA-biotin binding

Y Shi, C Pan, K Wang, Y Liu, Y Sun, Y Guo, P Sun… - Nanomaterials, 2022 - mdpi.com
Proteinaceous nanovaccine delivery systems have significantly promoted the development
of various high-efficiency vaccines. However, the widely used method of coupling the …

[HTML][HTML] Helicobacter pylori and microRNAs: Relation with innate immunity and progression of preneoplastic conditions

D Libânio, M Dinis-Ribeiro… - World journal of clinical …, 2015 - ncbi.nlm.nih.gov
The accepted paradigm for intestinal-type gastric cancer pathogenesis is a multistep
progression from chronic gastritis induced by Helicobacter pylori (H. pylori) to gastric …

[HTML][HTML] Therapeutic Protection Against H. pylori Infection in Mongolian Gerbils by Oral Immunization With a Tetravalent Epitope-Based Vaccine With Polysaccharide …

L Guo, D Hong, S Wang, F Zhang, F Tang… - Frontiers in …, 2019 - frontiersin.org
Urease is an effective target for design of a therapeutic epitope vaccine against Helicobacter
pylori (H. pylori). In our previous studies, an epitope vaccine CTB-UE containing Th and B …