[HTML][HTML] An overview of systemic lupus erythematosus (SLE) pathogenesis, classification, and management

MA Ameer, H Chaudhry, J Mushtaq, OS Khan, M Babar… - Cureus, 2022 - ncbi.nlm.nih.gov
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem
involvement. It is multifactorial and involves epigenetic, genetic, ecological, and …

[HTML][HTML] An expert consensus framework for asthma remission as a treatment goal

A Menzies-Gow, M Bafadhel, WW Busse… - Journal of Allergy and …, 2020 - Elsevier
With novel therapies in development, there is an opportunity to consider asthma remission
as a treatment goal. In this Rostrum, we present a generalized framework for clinical and …

Clinical and immunological biomarkers for systemic lupus erythematosus

H Yu, Y Nagafuchi, K Fujio - Biomolecules, 2021 - mdpi.com
Systemic lupus erythematosus (SLE) is characterized by immune system dysfunction and is
clinically heterogeneous, exhibiting renal, dermatological, neuropsychiatric, and …

Where microneedle meets biomarkers: futuristic application for diagnosing and monitoring localized external organ diseases

A Himawan, LK Vora, AD Permana… - Advanced …, 2023 - Wiley Online Library
Extracellular tissue fluids are interesting biomatrices that have recently attracted scientists'
interest. Many significant biomarkers for localized external organ diseases have been …

The emerging functions of long noncoding RNA in immune cells: autoimmune diseases

KR Sigdel, A Cheng, Y Wang, L Duan… - Journal of immunology …, 2015 - Wiley Online Library
The long noncoding RNAs (lncRNAs) are RNA transcripts more than 200 nucleotides in
length, which do not encode proteins. The lncRNAs are emerging as an important regulator …

IL-12 and IL-23/Th17 axis in systemic lupus erythematosus

M Larosa, M Zen, M Gatto, D Jesus… - Experimental …, 2019 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a very complex disease where multiple
immunological pathways can concur in inducing tissue damage. Cytokines are key …

Mechanisms and functions of mitophagy and potential roles in renal disease

Z Zuo, K Jing, H Wu, S Wang, L Ye, Z Li… - Frontiers in …, 2020 - frontiersin.org
Mitophagy is an evolutionarily conserved process to selectively remove damaged or
unnecessary mitochondria via the autophagic machinery. In this review, we focus on recent …

Autoantibodies-enemies, and/or potential allies?

H Ma, C Murphy, CE Loscher… - Frontiers in Immunology, 2022 - frontiersin.org
Autoantibodies are well known as potentially highly harmful antibodies which attack the host
via binding to self-antigens, thus causing severe associated diseases and symptoms (eg …

Systemic lupus erythematosus: the search for the ideal biomarker

LA González, MF Ugarte-Gil, GS Alarcón - Lupus, 2021 - journals.sagepub.com
During the last decades, there has been an increased interest in the discovery and
validation of biomarkers that reliably reflect specific aspects of lupus. Although many …

The extent of tubulointerstitial inflammation is an independent predictor of renal survival in lupus nephritis

MF Gomes, C Mardones, M Xipell, M Blasco… - Journal of …, 2021 - Springer
Background and objective Lupus nephritis (LN) is a major complication in patients with
systemic lupus erythematosus (SLE). Tubulointerstitial injury is an inflammatory process that …