During the last decade, owing to the low effectiveness and high toxicity of older antifungals,
new antifungal agents have been released to the market for the treatment of patients with …

The synthesis and antifungal activity of 2-acylhydrazino-5-arylpyrroles 21–62 are described.
Pyrrole derivatives 21–62 were evaluated for their antifungal activity towards Candida …

Fifteen 2-[(substituted-benzylidene)-amino]-5-methyl-thiophene-3-carbonitrile (3a-g) and 2-
[(sub-stituted-benzylidene)-amino]-4, 5-cycloalkyl-thiophene-3-carbonitrile derivatives (4a-h) …

We have identified a P450cam mutation, L244A, that mitigates the affinity for imidazole and
substituted imidazoles while maintaining a high affinity for the natural substrate camphor …

A series of new amine cyanoborane derivatives were synthesized and exhibited antifungal
activity. A long alkyl chain attached to the nitrogen of the amine cyanoboranes and …

The use of antibiotics or antifungals to control infections caused by pathogenic
microorganisms is currently insufficiently effective because of their emerging resistance …

Objective: The aim of this report is to describe a case with Aspergillus vertebral osteomyelitis
complicating pulmonary granuloma in an immunocompetent adult. Clinical Presentation and …

Background: Invasive pulmonary aspergillosis (IPA) remains a life-threatening condition
despite systemic antifungal therapy. Objectives: This retrospective analysis investigated …

Altough the therapy of fungal infections has been developing for many years, searching of
optimal drugs and pharmacotherapeutic approach is still desirable due to the increasing …

Microbial biofilm is a major source of problems and microbial contamination across the
industrial production, for example in pharmacy, agriculture or food industry, but also in …