[HTML][HTML] SARS-CoV-2 genomic surveillance in Brazil: a systematic review with scientometric analysis

D Menezes, PLC Fonseca, JLF de Araújo, RP Souza - Viruses, 2022 - mdpi.com
Several studies have monitored the SARS-CoV-2 variants in Brazil throughout the
pandemic. Here, we systematically reviewed and conducted a scientometric analysis of the …

The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the spike protein

PC Resende, FG Naveca, RD Lins, FZ Dezordi… - Virus …, 2021 - academic.oup.com
Mutations at both the receptor-binding domain (RBD) and the amino (N)-terminal domain
(NTD) of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike (S) …

[HTML][HTML] Final results of a randomized, placebo-controlled, two-arm, parallel clinical trial of proxalutamide for hospitalized COVID-19 patients: a multiregional, joint …

FA Cadegiani, RA Zimerman, DN Fonseca, MN Correia… - Cureus, 2021 - ncbi.nlm.nih.gov
Background The role of androgens on COVID-19 is well established. Proxalutamide is a
second-generation, non-steroidal antiandrogen (NSAA) with the highest antiandrogen …

Epidemiological dynamics of SARS-CoV-2 VOC gamma in Rio de Janeiro, Brazil

FRR Moreira, M D'arc, D Mariani, AL Herlinger… - Virus …, 2021 - academic.oup.com
The emergence and widespread circulation of severe acute respiratory syndrome
coronavirus 2 variants of concern (VOCs) or interest impose an enhanced threat to global …

Follow-up investigation and detailed mutational characterization of the SARS-CoV-2 Omicron variant lineages (BA. 1, BA. 2, BA. 3 and BA. 1.1)

Q Abbas, A Kusakin, K Sharrouf, S Jyakhwo… - biorxiv, 2022 - biorxiv.org
Aided by extensive protein mutations, the SARS-CoV-2 Omicron (B. 1.1. 529) variant
overtook the previously dominant Delta variant and rapidly spread around the world. It was …

[HTML][HTML] Evolutionary history of the SARS-CoV-2 Gamma variant of concern (P. 1): a perfect storm

Y Yépez, M Marcano-Ruiz, RS Bezerra… - … and molecular biology, 2022 - SciELO Brasil
Our goal was to describe in more detail the evolutionary history of Gamma and two derived
lineages (P. 1.1 and P. 1.2), which are part of the arms race that SARS-CoV-2 wages with its …

Spatiotemporal transmission of SARS-CoV-2 lineages during 2020–2021 in Pernambuco—Brazil

LC Machado, FZ Dezordi, GB de Lima… - Microbiology …, 2024 - Am Soc Microbiol
ABSTRACT SARS-CoV-2 virus emerged as a new threat to humans and spread around the
world, leaving a large death toll. As of January 2023, Brazil is among the countries with the …

Associations between epidemiological and laboratory parameters and disease severity in hospitalized patients with COVID-19 during first and second epidemic …

TCD da Cruz, JAR Pavon, FSK de Azevedo… - Brazilian Journal of …, 2024 - Springer
Background COVID-19 is a multisystemic disease characterized by respiratory distress.
Disease severity is associated with several factors. Here we characterize virological findings …

[HTML][HTML] Genomic characterization and molecular evolution of SARS-CoV-2 in Rio Grande do Sul State, Brazil

A de Menezes Mayer, PAG Ferrareze, LFV de Oliveira… - Virology, 2023 - Elsevier
SARS-CoV-2 is the virus responsible for the COVID-19 and has afflicted the world since the
end of 2019. Different lineages have been discovered and the Gamma lineage, which …

RNA-binding domain of SARS-CoV2 nucleocapsid: MD simulation study of the effect of the proline substitutions P67S and P80R on the structure of the protein

M Manish, M Pahuja, AM Lynn… - Journal of Biomolecular …, 2024 - Taylor & Francis
The nucleocapsid component of SARS-CoV2 is involved in the viral genome packaging.
GammaP. 1 (Brazil) and the 20 C-US (USA) variants had a high frequency of the P80R and …