Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

The growing field of immunometabolism has taught us how metabolic cellular reactions and
processes not only provide a means to generate ATP and biosynthetic precursors, but are …

Abstract Hypoxia‐inducible factor 1 (HIF‐1) plays an indispensable role in the hypoxic tumor
microenvironment. Hypoxia and HIF‐1 are involved in multiple aspects of tumor progression …

Obesity is a global epidemic representing a serious public health burden as it is a major risk
factor for the development of cardiovascular disease, stroke and all-cause mortality. Chronic …

The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Ligusticum chuanxiong Hort (known as Chuanxiong in China, CX) is one of the most widely
used and long-standing medicinal herbs in China. Tetramethylpyrazine (TMP) is an alkaloid …

Abstract Di-(2-ethylhexyl) phthalate (DEHP) is an extensively used plasticizer and has been
shown to cause reproductive dysfunction in humans and model animals. However, the exact …

The correct concentration of oxygen in all tissues is a hallmark of cellular wellness, and the
negative regulation of oxygen homeostasis is able to affect the cells and tissues of the whole …

Carbonic anhydrases IX and CAXII (CAIX/CAXII) are transmembrane zinc metalloproteins
that catalyze a very basic but crucial physiological reaction: the conversion of carbon dioxide …

Abstract Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following
ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate …