[HTML][HTML] Betamethasone phosphate reduces the efficacy of antenatal steroid therapy and is associated with lower birthweights when administered to pregnant sheep …

T Takahashi, EL Fee, Y Takahashi, M Saito… - American journal of …, 2022 - Elsevier
Background Antenatal corticosteroid therapy is a standard of care for women at imminent
risk of preterm labor. However, the optimal (maximum benefit and minimal risk of side …

A growing dilemma: antenatal corticosteroids and long-term consequences

EV Asztalos, KE Murphy… - American Journal of …, 2022 - thieme-connect.com
Objective A single course of synthetic antenatal corticosteroids is standard care for women
considered to be at risk for preterm birth before 34 weeks of gestation. While the intended …

[HTML][HTML] Association between antenatal corticosteroid treatment and severe adverse events in pregnant women

HJ Tsai, BI Wallace, AK Waljee, X Hong, SM Chang… - BMC medicine, 2023 - Springer
Background Antenatal corticosteroids are considered the standard of care for pregnant
women at risk for preterm birth, but studies examining their potential risks are scarce. We …

Antenatal corticosteroids prior to planned caesarean at term for improving neonatal outcomes

A Sotiriadis, E McGoldrick… - Cochrane Database …, 2021 - cochranelibrary.com
Background Infants born at term by elective caesarean section are more likely to develop
respiratory morbidity than infants born vaginally. Prophylactic corticosteroids in singleton …

Respiratory benefit in preterm lambs is progressively lost when the concentration of fetal plasma betamethasone is titrated below two nanograms per milliliter

EL Fee, T Takahashi, Y Takahashi… - … of Physiology-Lung …, 2023 - journals.physiology.org
Antenatal steroid therapy is the standard of care for women at imminent risk of preterm
delivery. Current dosing regimens use suprapharmacological doses to achieve extended …

How can obstetricians improve outcomes for infants born extremely preterm?

SC Kane, KM Groom, CA Crowther - Seminars in Perinatology, 2021 - Elsevier
Prematurity remains a leading cause of perinatal morbidity and mortality, and also has
significant implications for long-term health. Obstetricians have a key role to play in …

Different corticosteroids and regimens for accelerating fetal lung maturation for babies at risk of preterm birth

MJ Williams, JA Ramson… - Cochrane Database of …, 2022 - cochranelibrary.com
Background Despite the widespread use of antenatal corticosteroids to prevent respiratory
distress syndrome (RDS) in preterm infants, there is currently no consensus as to the type of …

Partially clustered designs for clinical trials: Unifying existing designs using consistent terminology

KM Lange, J Kasza, TR Sullivan, LN Yelland - Clinical Trials, 2023 - journals.sagepub.com
Introduction: Clinical trial designs based on the assumption of independent observations are
well established. Clustered clinical trial designs, where all observational units belong to a …

Antenatal corticosteroids: an updated assessment of anticipated benefits and potential risks

AH Jobe, RL Goldenberg, MW Kemp - American Journal of Obstetrics and …, 2024 - Elsevier
Antenatal steroid therapy is increasingly central to the obstetrical management of women at
imminent risk of preterm birth. For women likely to deliver between 24 and 34 weeks' …

[HTML][HTML] The complex challenge of antenatal steroid therapy nonresponsiveness

T Takahashi, AH Jobe, EL Fee, JP Newnham… - American journal of …, 2022 - Elsevier
Antenatal steroid therapy is standard care for women at imminent risk of preterm delivery.
When deliveries occur within 7 days of treatment, antenatal steroid therapy reduces the risk …