Antimicrobial peptides immune modulation role in intracellular bacterial infection
DI Duarte-Mata, MC Salinas-Carmona - Frontiers in Immunology, 2023 - frontiersin.org
Intracellular bacteria cause a wide range of diseases, and their intracellular lifestyle makes
infections difficult to resolve. Furthermore, standard therapy antibiotics are often unable to …
infections difficult to resolve. Furthermore, standard therapy antibiotics are often unable to …
Granulocytes subsets and their divergent functions in host resistance to Mycobacterium tuberculosis—a 'tipping-point'model of disease exacerbation
KD Mayer-Barber - Current Opinion in Immunology, 2023 - Elsevier
Granulocytes are innate immune effector cells with essential functions in host resistance to
bacterial infections. I will discuss emerging evidence that during Mycobacterium tuberculosis …
bacterial infections. I will discuss emerging evidence that during Mycobacterium tuberculosis …
Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …
propagate and cause fatal diseases. The microbes overpower host immunity at various …
Pulmonary MTBVAC vaccination induces immune signatures previously correlated with prevention of tuberculosis infection
K Dijkman, N Aguilo, C Boot, SO Hofman… - Cell Reports …, 2021 - cell.com
To fight tuberculosis, better vaccination strategies are needed. Live attenuated
Mycobacterium tuberculosis-derived vaccine, MTBVAC, is a promising candidate in the …
Mycobacterium tuberculosis-derived vaccine, MTBVAC, is a promising candidate in the …
Mycobacterium tuberculosis PE/PPE proteins enhance the production of reactive oxygen species and formation of neutrophil extracellular traps
M García-Bengoa, M Meurer, M Stehr… - Frontiers in …, 2023 - frontiersin.org
Introduction Neutrophil granulocytes predominate in the lungs of patients infected with
Mycobacterium tuberculosis (Mtb) in earlier stages of the disease. During infection …
Mycobacterium tuberculosis (Mtb) in earlier stages of the disease. During infection …
[HTML][HTML] The immune response in tubercular uveitis and its implications for treatment: From anti-tubercular treatment to host-directed therapies
I Putera, B Schrijver, JCEM Ten Berge, V Gupta… - Progress in Retinal and …, 2023 - Elsevier
Tubercular uveitis (TB-uveitis) remains a conundrum in the uveitis field, which is mainly
related to the diverse clinical phenotypes of TB-uveitis. Moreover, it remains difficult to …
related to the diverse clinical phenotypes of TB-uveitis. Moreover, it remains difficult to …
Platelet activation and the immune response to tuberculosis
DE Kirwan, DLW Chong, JS Friedland - Frontiers in Immunology, 2021 - frontiersin.org
In 2019 10 million people developed symptomatic tuberculosis (TB) disease and 1.2 million
died. In active TB the inflammatory response causes tissue destruction, which leads to both …
died. In active TB the inflammatory response causes tissue destruction, which leads to both …
Tweaking host immune responses for novel therapeutic approaches against Mycobacterium tuberculosis
In TB, combat between the human host and Mycobacterium tuberculosis involves intricate
interactions with immune cells. M. tuberculosis has evolved a complex evasion system to …
interactions with immune cells. M. tuberculosis has evolved a complex evasion system to …
Viral coinfection promotes tuberculosis immunopathogenesis by type I IFN signaling-dependent impediment of Th1 cell pulmonary influx
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is often exacerbated upon
coinfection, but the underlying immunological mechanisms remain unclear. Here, to …
coinfection, but the underlying immunological mechanisms remain unclear. Here, to …
Molecular and Cellular Mechanisms of M. tuberculosis and SARS-CoV-2 Infections—Unexpected Similarities of Pathogenesis and What to Expect from Co-Infection
AA Starshinova, I Kudryavtsev, A Malkova… - International Journal of …, 2022 - mdpi.com
Tuberculosis is still an important medical and social problem. In recent years, great strides
have been made in the fight against M. tuberculosis, especially in the Russian Federation …
have been made in the fight against M. tuberculosis, especially in the Russian Federation …