Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis

F Damas, CA Libardi, C Ugrinowitsch - European journal of applied …, 2018 - Springer
Resistance training (RT)-induced skeletal muscle hypertrophy is a highly intricate process.
Despite substantial advances, we are far from understanding exactly how muscle …

Myokines and resistance training: a narrative review

BEM Zunner, NB Wachsmuth, ML Eckstein… - International journal of …, 2022 - mdpi.com
In the last few years, the muscular system has gained attention due to the discovery of the
muscle-secretome and its high potency for retaining or regaining health. These cytokines …

Molecular mechanisms of skeletal muscle hypertrophy

S Schiaffino, C Reggiani, T Akimoto… - Journal of …, 2021 - content.iospress.com
Skeletal muscle hypertrophy can be induced by hormones and growth factors acting directly
as positive regulators of muscle growth or indirectly by neutralizing negative regulators, and …

Satellite cells in ageing: use it or lose it

W Chen, D Datzkiw, MA Rudnicki - Open biology, 2020 - royalsocietypublishing.org
Individuals that maintain healthy skeletal tissue tend to live healthier, happier lives as proper
muscle function enables maintenance of independence and actuation of autonomy. The …

Exercise and the control of muscle mass in human

M Francaux, L Deldicque - Pflügers Archiv-European Journal of Physiology, 2019 - Springer
During the course of life, muscle mass undergoes many changes in terms of quantity and
quality. Skeletal muscle is a dynamic tissue able to hypertrophy or atrophy according to …

Role of mTORC1 in mechanically induced increases in translation and skeletal muscle mass

CA Goodman - Journal of applied physiology, 2019 - journals.physiology.org
Skeletal muscle mass is, in part, regulated by the rate of mRNA translation (ie, protein
synthesis). The conserved serine/threonine kinase, mTOR (the mammalian/mechanistic …

Accelerometer derived physical activity patterns in 27.890 middle‐aged adults: the SCAPIS cohort study

E Ekblom‐Bak, M Börjesson, F Bergman… - … journal of medicine …, 2022 - Wiley Online Library
The present study aims to describe accelerometer‐assessed physical activity (PA) patterns
and fulfillment of PA recommendations in a large sample of middle‐aged men and women …

[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions

KM Lavin, PM Coen, LC Baptista, MB Bell… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Differences in muscle satellite cell dynamics during muscle hypertrophy and regeneration

S Fukada, T Higashimoto, A Kaneshige - Skeletal muscle, 2022 - Springer
Skeletal muscle homeostasis and function are ensured by orchestrated cellular interactions
among several types of cells. A noticeable aspect of skeletal muscle biology is the drastic …