Dynamic contrast‐enhanced MRI in clinical oncology: current status and future directions

AR Padhani - Journal of Magnetic Resonance Imaging: An …, 2002 - Wiley Online Library
Dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI) is performed after the
administration of intravenous contrast medium to noninvasively access tumor vascular …

Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target

RL Jensen - Journal of neuro-oncology, 2009 - Springer
Hypoxia is implicated in many aspects of tumor development, angiogenesis, and growth in
many different tumors. Brain tumors, particularly the highly aggressive glioblastoma …

Dynamic contrast-enhanced MRI studies in oncology with an emphasis on quantification, validation and human studies

AR Padhani, JE Husband - Clinical radiology, 2001 - Elsevier
Magnetic resonance imaging (MRI), after the administration of an extracellular, gadolinium-
based contrast medium, can be used to detect and characterize human tumours. The …

CT Perfusion for the Monitoring of Neoadjuvant Chemotherapy and Radiation Therapy in Rectal Carcinoma: Initial Experience1

M Bellomi, G Petralia, A Sonzogni, MG Zampino… - Radiology, 2007 - pubs.rsna.org
Purpose: To prospectively monitor changes in rectal cancer perfusion after combined
neoadjuvant chemotherapy and radiation therapy with perfusion computed tomography (CT) …

Angiogenesis modulation in cancer research: novel clinical approaches

M Cristofanilli, C Charnsangavej… - Nature reviews Drug …, 2002 - nature.com
Angiogenesis—the formation of new blood vessels—is essential for tumour progression and
metastasis. Consequently, the modulation of tumour angiogenesis using novel agents has …

Imaging hypoxia and angiogenesis in tumors

JG Rajendran, KA Krohn - Radiologic Clinics, 2005 - radiologic.theclinics.com
Advances in molecular imaging are rapidly changing the paradigm for noninvasive
diagnostic imaging from largely morphologic methods to ones that include both anatomy …

Nuclear medicine applications in molecular imaging

FG Blankenberg, HW Strauss - Journal of Magnetic Resonance …, 2002 - Wiley Online Library
With the emergence of the new field of molecular imaging, there is an increasing demand for
development of sensitive and safe novel imaging agents that can be rapidly translated from …

Imaging hypoxia in gliomas

I Mendichovszky, A Jackson - The British journal of radiology, 2011 - academic.oup.com
Hypoxia plays a central role in tumour development, angiogenesis, growth and resistance to
treatment. Owing to constant developments in medical imaging technology, significant …

Whole-animal cellular and molecular imaging to accelerate drug development

PR Contag - Drug discovery today, 2002 - Elsevier
In the past decade, new technologies (genomics), chemistries and high-throughput (HT) in
vitro assays have played a large role in changing the paradigm of drug discovery and …

Molecular (functional) imaging for radiotherapy applications: an RTOG symposium

JD Chapman, JD Bradley, JF Eary, R Haubner… - International Journal of …, 2003 - Elsevier
The Translational Research and Image-Guided Radiotherapy Committees of the Radiation
Therapy Oncology Group (RTOG) organized this symposium for the winter 2002 semiannual …