[HTML][HTML] Aquaporins in insulin resistance and diabetes: More than channels!

M Galli, A Hameed, A Żbikowski, P Zabielski - Redox biology, 2021 - Elsevier
Aquaporins (AQPs) are part of the family of the integral membrane proteins. Their function is
dedicated to the transport of water, glycerol, ammonia, urea, H 2 O 2, and other small …

Involvement of aquaglyceroporins in energy metabolism in health and disease

G Calamita, C Delporte - Biochimie, 2021 - Elsevier
Aquaglyceroporins are a group of the aquaporin (AQP) family of transmembrane water
channels. While AQPs facilitate the passage of water, small solutes, and gases across …

Aquaglyceroporins are differentially expressed in beige and white adipocytes

IV da Silva, F Díaz-Sáez, A Zorzano, A Gumà… - International Journal of …, 2020 - mdpi.com
Browning of white adipocytes has been proposed as a powerful strategy to overcome
metabolic complications, since brown adipocytes are more catabolic, expending energy as a …

PPARγ transcription deficiency exacerbates high-fat diet-induced adipocyte hypertrophy and insulin resistance in mice

F Guo, S Xu, Y Zhu, X Zheng, Y Lu, J Tu, Y He… - Frontiers in …, 2020 - frontiersin.org
Background The transcriptional factor peroxisome proliferator–activated receptor γ (PPARγ)
is an important therapeutic target for the treatment of type 2 diabetes. However, the role of …

Decreased adipocyte glucose transporter 4 (GLUT4) and aquaglyceroporin-7 (AQP7) in adults with morbid obesity: possible early markers of metabolic dysfunction

R Mourelatou, E Kostopoulou, AP Rojas-Gil, I Kehagias… - Hormones, 2019 - Springer
Abstract Purpose Morbid obesity (BMI> 40) is often accompanied by metabolic disorders. In
adipose tissue, serine/threonine kinase PKBβ/AktΙΙ plays a role in glucose uptake, mediated …

Biochemical and molecular study on pigment epithelium derived factor and aquaporin channel protein 7 gene expression in obese children

SS El-niadany, AM El-Torgoman, YA Elghobashy… - Human Gene, 2023 - Elsevier
Background and aim Genetic variables have a crucial function in the onset of pediatric
obesity. PEDF was implicated in the development of obesity, also the transmembrane …

Associations between aquaglyceroporin gene polymorphisms and risk of stroke among patients with hypertension

Q Tu, L Yan, C Wang, A Han, Y Qin… - BioMed Research …, 2020 - Wiley Online Library
Background. Dysregulations of AQP7 and AQP9 were found to be related to lipid
metabolism abnormality, which had been proven to be one of the mechanisms of stroke …

Genomic and expression characterization of aquaporin genes from Siniperca chuatsi

Y Shen, H Li, J Zhao, S Tang, Y Zhao, Y Gu… - … and Physiology Part D …, 2021 - Elsevier
Aquaporins (AQPs) are major intrinsic proteins that form pores in the membranes of
biological cells. We first cloned the full-length sequences of aqp0, 1, 3, 4, 7, 8, 9, 10, 11, and …

The metabolic implications of aquaporin 7 (AQP7) promoter variants in lean children and children with obesity

E Oikonomou, E Kostopoulou, AP Rojas-Gil… - Hormones, 2020 - Springer
Purpose AQP7, a water/glycerol transporting protein, regulates adipocyte glycerol efflux and
influences lipid and glucose homeostasis. Altered AQP7 expression in adults leads to …

[PDF][PDF] AQP 磁共振分子成像在肿瘤中的研究进展

肖刚, 胡玉川, 崔光彬 - Chin J Magn Reson Imaging, 2019 - med-sci.cn
水通道蛋白(aquaporins, AQPs) 是细胞膜上选择性转运水分子的膜内在蛋白,
广泛存在于生物体内各组织器官, 其生理状态的改变与许多疾病的发生发展密切相关 …