Salmonella enterica serovar Typhi and nontyphoidal Salmonella (NTS) cause the majority of
bloodstream infections in sub-Saharan Africa; however, serotyping is rarely performed. We …

Background Clearly differentiating causes of fever is challenging where diagnostic
capacities are limited, resulting in poor patient management. We investigated acute febrile …

Salmonella Typhi is the causative agent of typhoid. Typhoid is diagnosed by blood culture, a
method that lacks sensitivity, portability and speed. We have previously shown that specific …

Objective The aim of this study was to compare laboratory surveillance with the notifiable
diseases surveillance system (NDSS) in South Africa. Methods Data on three tracer …

Background With more than 1.2 million illnesses and 29,000 deaths in sub-Saharan Africa in
2017, typhoid fever continues to be a major public health problem. Effective control of the …

Acute febrile illness (AFI) is a broad clinical syndrome with a wide range of potential
infectious etiologies. The lack of accessible, standardized approaches to conducting AFI …

Abstract Background Invasive non-typhoidal Salmonella (iNTS) is a growing health-concern
in many parts of sub-Saharan Africa. iNTS is associated with fatal diseases such as HIV and …

Quantitative polymerase chain reaction (qPCR) of dried blood spots (DBS) for pathogen
detection is a potentially convenient method for infectious disease diagnosis. This study …

Rickettsiae may cause febrile infections in humans in tropical and subtropical regions. From
Madagascar, no molecular data on the role of rickettsioses in febrile patients are available …

ABSTRACT Background: Plasmodium falciparum and Salmonella typhi are major causes of
fever in the tropics. Although these infections are caused by different organisms and are …