Animal experimentation is necessary to characterize human diseases and design adequate
therapeutic interventions. In renal transplantation research, the limited number of in vitro …

Inflammatory reactions in the graft have a pivotal influence on acute as well as long-term
graft function. The main reasons for an inflammatory reaction of the graft tissue are rejection …

The realization of long-term human organ preservation will have groundbreaking effects on
the current practice of transplantation. Herein we present a new technique based on …

Objective: Unexpected donation after cardiac death (DCD) donors suffer cardiac arrest
suddenly and are maintained with normothermic extracorporeal membrane oxygenation …

The increased demand for organs has led to the increased usage of “higher risk” kidney and
liver grafts. These grafts from donation after circulatory death or expanded criteria donors …

Background. Hypothermic machine perfusion (HMP) has become standard care in many
center's to preserve kidneys donated after circulatory death (DCD). Despite a significant …

Optimizing kidney preservation is a primary issue in transplantation, particularly in relation to
new donor sources, such as expanded criteria donors (ECDs) and donation after cardiac …

The final decision to accept an organ for transplantation remains a subjective one. With
“poor organ quality” commonly cited as a major reason for kidney discard, accurate …

Background Deceased after cardiac death donors (DCDs) represent a valuable source of
organs; however, preventing poor outcome is difficult, even with the use of machine …

Background: The two main options for renal allograft preservation are static cold storage
(CS) and machine perfusion (MP). There has been considerably increased interest in MP …