Vascular calcification—new insights into its mechanism

SJ Lee, IK Lee, JH Jeon - International journal of molecular sciences, 2020 - mdpi.com
Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

AL Durham, MY Speer, M Scatena… - Cardiovascular …, 2018 - academic.oup.com
Vascular calcification is associated with a significant increase in all-cause mortality and
atherosclerotic plaque rupture. Calcification has been determined to be an active process …

Kidney stones

SR Khan, MS Pearle, WG Robertson… - Nature reviews Disease …, 2016 - nature.com
Kidney stones are mineral deposits in the renal calyces and pelvis that are found free or
attached to the renal papillae. They contain crystalline and organic components and are …

Atherosclerosis in chronic kidney disease: more, less, or just different?

JM Valdivielso, D Rodríguez-Puyol… - … , and vascular biology, 2019 - Am Heart Assoc
Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality,
mainly from cardiovascular causes. The association between CKD on hemodialysis and …

Interaction between hypertension and arterial stiffness: an expert reappraisal

ME Safar, R Asmar, A Benetos, J Blacher… - …, 2018 - Am Heart Assoc
Safar et al Hypertension and Arterial Stiffness 797 amplification, though it actually refers to a
pressure waveform distortion rather than an amplification, the latter erroneously implying an …

Medial vascular calcification revisited: review and perspectives

P Lanzer, M Boehm, V Sorribas, M Thiriet… - European heart …, 2014 - academic.oup.com
Vascular calcifications (VCs) are actively regulated biological processes associated with
crystallization of hydroxyapatite in the extracellular matrix and in cells of the media (VCm) or …

An update on the phenotypic switching of vascular smooth muscle cells in the pathogenesis of atherosclerosis

F Zhang, X Guo, Y Xia, L Mao - Cellular and Molecular Life Sciences, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are involved in phenotypic switching in
atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, and …

Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolism

MC Hu, K Shiizaki, M Kuro-o… - Annual review of …, 2013 - annualreviews.org
The metabolically active and perpetually remodeling calcium phosphate–based
endoskeleton in terrestrial vertebrates sets the demands on whole-organism calcium and …

Secondary hyperparathyroidism: pathogenesis, disease progression, and therapeutic options

J Cunningham, F Locatelli… - Clinical Journal of the …, 2011 - journals.lww.com
Secondary hyperparathyroidism (SHPT) is a challenge frequently encountered in the
management of patients with chronic kidney disease (CKD). Downregulation of the …

Chronic kidney disease and cardiovascular complications

L Di Lullo, A House, A Gorini, A Santoboni, D Russo… - Heart failure …, 2015 - Springer
Cardiovascular diseases such as coronary artery disease, congestive heart failure,
arrhythmias and sudden cardiac death represent main causes of morbidity and mortality in …