Redefining cerebral palsies as a diverse group of neurodevelopmental disorders with genetic aetiology

CL van Eyk, MC Fahey, J Gecz - Nature Reviews Neurology, 2023 - nature.com
Cerebral palsy is a clinical descriptor covering a diverse group of permanent, non-
degenerative disorders of motor function. Around one-third of cases have now been shown …

[HTML][HTML] Insights from genetic studies of cerebral palsy

SA Lewis, S Shetty, BA Wilson, AJ Huang… - Frontiers in …, 2021 - frontiersin.org
Cohort-based whole exome and whole genome sequencing and copy number variant
(CNV) studies have identified genetic etiologies for a sizable proportion of patients with …

Comprehensive whole-genome sequence analyses provide insights into the genomic architecture of cerebral palsy

DL Fehlings, M Zarrei, W Engchuan, N Sondheimer… - Nature Genetics, 2024 - nature.com
We performed whole-genome sequencing (WGS) in 327 children with cerebral palsy (CP)
and their biological parents. We classified 37 of 327 (11.3%) children as having …

[HTML][HTML] Yield of clinically reportable genetic variants in unselected cerebral palsy by whole genome sequencing

CL van Eyk, DL Webber, AE Minoche… - NPJ genomic …, 2021 - nature.com
Cerebral palsy (CP) is the most common cause of childhood physical disability, with
incidence between 1/500 and 1/700 births in the developed world. Despite increasing …

[HTML][HTML] The role of neuroimaging and genetic analysis in the diagnosis of children with cerebral palsy

V Horber, U Grasshoff, E Sellier, C Arnaud… - Frontiers in …, 2021 - frontiersin.org
Cerebral magnetic resonance imaging (MRI) is considered an important tool in the
assessment of a child with cerebral palsy (CP), as it is abnormal in more than 80% of …

A Robust Fuzzy Fractional Order PID Design Based On Multi-Objective Optimization For Rehabilitation Device Control

I Zaway, R Jallouli-Khlif, B Maalej… - Journal of Robotics and …, 2023 - journal.umy.ac.id
Abstract In this context, Fuzzy Fractional Order Proportional Integral Derivative (FOPID-FLC)
controllers are emerged as efficient approaches due to their flexibility and ability to handle …

[HTML][HTML] Precision autism: genomic stratification of disorders making up the broad spectrum may demystify its “Epidemic Rates”

EB Torres - Journal of Personalized Medicine, 2021 - mdpi.com
In the last decade, Autism has broadened and often shifted its diagnostics criteria, allowing
several neuropsychiatric and neurological disorders of known etiology. This has resulted in …

[HTML][HTML] Cortisol levels in infants with central coordination disorders during Vojta therapy

W Kiebzak, A Żurawski, S Głuszek, M Kosztołowicz… - Children, 2021 - mdpi.com
Background: Due to the decrease in the percentage of perinatal mortality, which is one of the
Millennium Development Goals, the number of children with a central coordination disorder …

Making waves: The changing tide of cerebral palsy

MS Cooper, MC Fahey… - Journal of Paediatrics and …, 2022 - Wiley Online Library
Cerebral palsy (CP) is a broad diagnosis unbound by aetiology and is based on a clinical
examination demonstrating abnormalities of movement or posture. CP represents a static …

儿童和青少年脑性瘫痪临床实践指南选题的范围综述

史惟, 张崇凡, 黄真, 肖农, 朱登纳, 徐开寿, 王素娟… - 中国循证儿科杂志, 2022 - cjebp.net
背景: 儿童和青少年脑瘫的康复期望高质量的临床实践指南, 指导康复实践者通过科学合理的
评估与干预, 改善儿童和青少年脑瘫的健康状态. 目的支持, 改进和完善指南核心专家组提出的 …