Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

Executive summary Despite the improvements in outcomes for cardiovascular disease
(CVD) over the last 20 years, it remains the major cause of morbidity and mortality in the …

Background Increases in lipid levels and cancers with tofacitinib prompted a trial of major
adverse cardiovascular events (MACE) and cancers in patients with rheumatoid arthritis …

Objectives Evaluate risk of major adverse cardiovascular events (MACE) with tofacitinib
versus tumour necrosis factor inhibitors (TNFi) in patients with rheumatoid arthritis (RA) with …

A variety of systemic inflammatory rheumatic diseases associate with an increased risk of
atherosclerotic events and premature cardiovascular (CV) disease. Although this recognition …

Rheumatoid arthritis (RA) is a chronic immuno-mediated disease primarily affecting the
joints, characterized by persistent high-grade systemic inflammation. Cardiovascular …

IL-6 has been linked to numerous diseases associated with inflammation, including
rheumatoid arthritis, inflammatory bowel disease, vasculitis and several types of cancer …

Rheumatoid arthritis (RA) is an autoimmune disease, which not only affects the joints but
can also impact on general well-being and risk for cardiovascular disease. Regular physical …

Patients with Chronic Inflammatory Rheumatic diseases (CIRD) are at increased risk of
cardiovascular disease (CVD), ascribed not only to classical risk factors, but also to the …

Objective This study was undertaken to assess the predictive ability of 4 established
cardiovascular (CV) risk models for the 10-year risk of fatal and non-fatal CV diseases in …